APPL1

Gene Symbol	APPL1
Entrez Gene	26060
Alt Symbol	APPL, DIP13alpha
Species	Human
Gene Type	protein-coding
Description	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Other Description	AKT2 interactor|DCC-interacting protein 13-alpha|adapter protein containing PH domain, PTB domain and leucine zipper motif 1|adaptor protein containing pH domain, PTB domain and leucine zipper motif 1|dip13-alpha|signaling adaptor protein DIP13alpha
Swissprots	Q9P2B9 Q9UKG1
Accessions	EAW65335 EAW65336 Q9UKG1 AB037849 BAA92666 AF169797 AAF04012 AF424738 AAL17835 AK299008 BAG61090 AK310716 BC010911 BC028599 AAH28599 JF432301 ADZ15518 XM_011533583 XP_011531885 NM_012096 NP_036228
Function	Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. {ECO:0000269|PubMed:10490823, ECO:0000269|PubMed:15016378}.
Subcellular Location	Early endosome membrane; Peripheral membrane protein. Nucleus. Note=Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
Tissue Specificity	High levels in heart, ovary, pancreas and skeletal muscle. {ECO:0000269|PubMed:10490823}.
Top Pathways	Colorectal cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

APPL1 siRNA gene - orb219200 from Biorbyt Prices $417.00 Sizes 5 od (260 nm) Species Human

Human-APPL1-cDNA-Clone - DC05846 from Abgent, a WuXi AppTec company Prices $957.15 Sizes 10 µg Species Human Accession BC028599

APPL1 - MBS1268288 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC028599

Human APPL1 ORF Clone(NM_012096.2) - CDCL154170 from Creative Biomart Species Human Accession NM_012096.2

Human APPL1 ORF Clone(NM_012096.2) - CDCR295378 from Creative Biomart Species Human Accession NM_012096.2

Human APPL1 ORF Clone(NM_012096.2) - CDCR295379 from Creative Biomart Species Human Accession NM_012096.2

Human APPL1 ORF Clone(NM_012096.2) - CDCR295380 from Creative Biomart Species Human Accession NM_012096.2

Human APPL1 ORF clone(NM_012096.2) - CDCL182731 from Creative Biomart Species Human Accession NM_012096.2

Human APPL1/APPL Gene ORF cDNA clone in cloning vector - HG11119-M from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, C-HA tag - HG11119-CY from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid - HG11119-UT from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, N-HA tag - HG11119-NY from Sino Biological Species Human

Human APPL1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG11119-NH from Sino Biological Species Human Accession NM_012096.2

Human APPL1 natural ORF mammalian expression plasmid, N-Flag tag - HG11119-NF from Sino Biological Species Human Accession NM_012096.2

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11119-NM from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11119-ANG from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11119-CF from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, C-His tag - HG11119-CH from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11119-CM from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11119-ANR from Sino Biological Species Human

Human APPL1 ORF clone(NM_012096.2) - CDCL182731 from Creative biogene Species Human

Human APPL1 ORF Clone (BC028599) - CDCS413195 from Creative biogene Species Human Accession Q9UKG1

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11119-ACG from Sino Biological Species Human

Human APPL1/APPL Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11119-ACR from Sino Biological Species Human

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