APPL1

Gene Symbol	APPL1
Entrez Gene	26060
Alt Symbol	APPL, DIP13alpha
Species	Human
Gene Type	protein-coding
Description	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Other Description	AKT2 interactor|DCC-interacting protein 13-alpha|adapter protein containing PH domain, PTB domain and leucine zipper motif 1|adaptor protein containing pH domain, PTB domain and leucine zipper motif 1|dip13-alpha|signaling adaptor protein DIP13alpha
Swissprots	Q9P2B9 Q9UKG1
Accessions	EAW65335 EAW65336 Q9UKG1 AB037849 BAA92666 AF169797 AAF04012 AF424738 AAL17835 AK299008 BAG61090 AK310716 BC010911 BC028599 AAH28599 JF432301 ADZ15518 XM_011533583 XP_011531885 NM_012096 NP_036228
Function	Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. {ECO:0000269|PubMed:10490823, ECO:0000269|PubMed:15016378}.
Subcellular Location	Early endosome membrane; Peripheral membrane protein. Nucleus. Note=Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
Tissue Specificity	High levels in heart, ovary, pancreas and skeletal muscle. {ECO:0000269|PubMed:10490823}.
Top Pathways	Colorectal cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human APPL peptide - ab23103 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

APPL1 / APPL Antibody Blocking Peptide - LS-E25593 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APPL1 / APPL Antibody Blocking Peptide - LS-E26249 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APPL1 / APPL Antibody Blocking Peptide - LS-E19769 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human APPL Protein - H00026060-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human APPL Protein - H00026060-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

APPL1-Antibody-C-term-Blocking-Peptide - BP9874b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

APPL1 blocking peptide - GTX89127-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

APPL1 Blocking Peptide - 33R-3487 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

APPL Peptide - AC21-1081-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

APPL Peptide - AC21-2800-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

APPL1 / DIP13A - H00026060-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

APPL1 / DIP13A - H00026060-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

APPL1 / DIP13A - H00026060-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

APPL1 / DIP13A - H00026060-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

APPL1 Peptide - 45-271P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

APPL1 fusion protein - Ag13703 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

APPL1 fusion protein - Ag3334 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

APPL1 fusion protein - ag13666 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human APPL1, His-tagged - APPL1-26345TH from Creative Biomart Category Protein Source E. coli

Recombinant Human APPL1, GST-tagged - APPL1-9774H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human APPL1, His-tagged - APPL1-1001H from Creative Biomart Category Protein Source E.Coli.

Recombinant Adaptor Protein Phosphotyrosine Interaction PH Domain And leucine Zipper Containing Protein 1 (APPL1) - RPL208Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Adaptor Protein Phosphotyrosine Interaction PH Domain And leucine Zipper Containing Protein 1 (APPL1) - RPL208Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human DCC-interacting protein 13-alpha(APPL1) - CSB-YP890917HU CSB-EP890917HU CSB-BP890917HU CSB-MP890917HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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