CLC

Gene Symbol	CLC
Entrez Gene	1178
Alt Symbol	GAL10, Gal-10, LGALS10, LGALS10A, LPPL_HUMAN
Species	Human
Gene Type	protein-coding
Description	Charcot-Leyden crystal galectin
Other Description	Charcot-Leyden crystal protein|eosinophil lysophospholipase|galectin 10|galectin-10|lectin, galactoside-binding, soluble, 10|lysolecithin acylhydrolase
Swissprots	Q0VDE3 C5HZ14 Q05315 C5HZ13
Accessions	AAC28912 AAC37530 AAC51157 EAW56914 Q05315 AV715261 AV762486 AW292557 BC119711 AAI19712 BC119712 AAI19713 FJ613334 ACR09636 FJ613335 ACR09637 L01664 AAA36190 NM_001828 NP_001819
Function	Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg). {ECO:0000269|PubMed:17502455}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000269|PubMed:17502455}. Cytoplasmic granule {ECO:0000269|PubMed:17502455}. Note=Localized in granules from where it may be secreted or transported to other locations in the cell.
Tissue Specificity	Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level). {ECO:0000269|PubMed:17502455, ECO:0000269|PubMed:19497882, ECO:0000269|PubMed:19758173, ECO:0000269|PubMed:22880030}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Galectin 10 full length protein - ab107951 from Abcam Category Protein Source E. coli Species Human

CLC-Antibody-C-term-Blocking-Peptide - BP14439b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLC-Antibody-C-term-Blocking-Peptide - BP16125b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLC protein (His tag) - 80R-1791 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Human CLC Protein - abx065856 from Abbexa Category Protein Source E.coli Species Human

Galectin-10 (1-142, His-tag) - AR09974PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Galectin-10 (1-142, His-tag) - AR09974PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Galectin-10 - H00001178-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Galectin-10 - H00001178-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Galectin-10 - P3578 from Acris Antibodies Category Protein Prices $500.00 Sizes 100 µg Species Human

Charcot Leyden Crystal Protein (CLC), Human - 20-8460 from ARP American Research Products Category Protein Prices $619.00 Sizes 50 µg Source E.coli Species Human

CLC, 1-142aa, Human, His tag, E.coli - 01-P1034 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

CLC fusion protein - ag18569 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CLC fusion protein - ag18668 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

LGALS10 Human - PRPS-751 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Galectin-10 Protein - BP002463-PRO-744 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

CLC, 1-142aa, Recombinant Protein - GWB-P1004C from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human Charcot-Leyden Crystal Protein, His-tagged - CLC-984H from Creative Biomart Category Protein

Recombinant Human CLC, His-tagged - CLC-28114TH from Creative Biomart Category Protein Source E. coli

Recombinant Human CLC, GST-tagged - CLC-11272H from Creative Biomart Category Protein Source E.coli Species Human

CLC 1-142aa - CMB-867 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 100.00 µg, 500 µg Source E.coli Species Human

LGALS10 - RP-NKX-199 from Reagent Proteins Category Protein Prices $364.00, $2,898.00 Sizes 20.00 µg, 1 mg Source E.coli

Recombinant Charcot Leyden Crystal Protein (CLC) - RPC387Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Charcot Leyden Crystal Protein (CLC) - RPC387Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Charcot Leyden Crystal Protein (CLC) - RPC387Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

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