CLC

Gene Symbol CLC
Entrez Gene 1178
Alt Symbol GAL10, Gal-10, LGALS10, LGALS10A, LPPL_HUMAN
Species Human
Gene Type protein-coding
Description Charcot-Leyden crystal galectin
Other Description Charcot-Leyden crystal protein|eosinophil lysophospholipase|galectin 10|galectin-10|lectin, galactoside-binding, soluble, 10|lysolecithin acylhydrolase
Swissprots Q0VDE3 C5HZ14 Q05315 C5HZ13
Accessions AAC28912 AAC37530 AAC51157 EAW56914 Q05315 AV715261 AV762486 AW292557 BC119711 AAI19712 BC119712 AAI19713 FJ613334 ACR09636 FJ613335 ACR09637 L01664 AAA36190 NM_001828 NP_001819
Function Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg). {ECO:0000269|PubMed:17502455}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:17502455}. Cytoplasmic granule {ECO:0000269|PubMed:17502455}. Note=Localized in granules from where it may be secreted or transported to other locations in the cell.
Tissue Specificity Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level). {ECO:0000269|PubMed:17502455, ECO:0000269|PubMed:19497882, ECO:0000269|PubMed:19758173, ECO:0000269|PubMed:22880030}.

galectin-10 CRISPR/Cas9 KO Plasmid (h) - sc-417735 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

galectin-10 HDR Plasmid (h) - sc-417735-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

galectin-10 Double Nickase Plasmid (h) - sc-417735-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

galectin-10 Double Nickase Plasmid (h2) - sc-417735-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

galectin-10 CRISPR Activation Plasmid (h) - sc-417735-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

galectin-10 CRISPR Activation Plasmid (h2) - sc-417735-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

galectin-10 Lentiviral Activation Particles (h) - sc-417735-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

galectin-10 Lentiviral Activation Particles (h2) - sc-417735-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

galectin-10 siRNA (h) - sc-72087 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

galectin-10 shRNA Plasmid (h) - sc-72087-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

galectin-10 shRNA (h) Lentiviral Particles - sc-72087-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU015271 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6163 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6163 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLC siRNA (Human) - CRH0840 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLC - MBS8229998 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLC (NM_001828.5) - SHH264485 from Creative biogene

Category siRNA
Species Reactivities Human

CLC shRNA Plasmid (Human) - CHH0840 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLC miRNA 3'UTR clone - MiUTR3H-01346 from Creative biogene

Species Reactivities Human
Search more