ENPP4

Gene Symbol ENPP4
Entrez Gene 22875
Alt Symbol NPP4
Species Human
Gene Type protein-coding
Description ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
Other Description AP3A hydrolase|AP3Aase|E-NPP 4|NPP-4|bis(5'-adenosyl)-triphosphatase ENPP4|ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)|ectonucleotide pyrophosphatase/phosphodiesterase family member 4
Swissprots Q9Y6X5 Q7L2N1 A8K5G1
Accessions CAJ78397 EAX04292 Q9Y6X5 AB020686 BAA74902 AJ420515 AK291276 BAF83965 BC018054 AAH18054 BI548305 CA433087 DA261977 DQ892332 ABM83258 DQ895537 ABM86463 NM_014936 NP_055751
Function Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors. {ECO:0000269|PubMed:22995898, ECO:0000269|PubMed:24338010}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22995898}; Single-pass type I membrane protein {ECO:0000269|PubMed:22995898}.
Tissue Specificity Expressed on the surface of vascular endothelia. {ECO:0000269|PubMed:22995898}.
Top Pathways Purine metabolism

ENPP4 293T Cell Transient Overexpression Lysate(Denatured) - H00022875-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

ENPP4 Overexpression Lysate (Denatured) - H00022875-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
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