ENPP4

Gene Symbol ENPP4
Entrez Gene 22875
Alt Symbol NPP4
Species Human
Gene Type protein-coding
Description ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
Other Description AP3A hydrolase|AP3Aase|E-NPP 4|NPP-4|bis(5'-adenosyl)-triphosphatase ENPP4|ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)|ectonucleotide pyrophosphatase/phosphodiesterase family member 4
Swissprots Q9Y6X5 Q7L2N1 A8K5G1
Accessions CAJ78397 EAX04292 Q9Y6X5 AB020686 BAA74902 AJ420515 AK291276 BAF83965 BC018054 AAH18054 BI548305 CA433087 DA261977 DQ892332 ABM83258 DQ895537 ABM86463 NM_014936 NP_055751
Function Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors. {ECO:0000269|PubMed:22995898, ECO:0000269|PubMed:24338010}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22995898}; Single-pass type I membrane protein {ECO:0000269|PubMed:22995898}.
Tissue Specificity Expressed on the surface of vascular endothelia. {ECO:0000269|PubMed:22995898}.
Top Pathways Purine metabolism

NPP4 (C-15) - sc-248107 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NPP4 (T-12) - sc-248105 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ENPP4 antibody - ab121505 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121505 at 1/40 dilution staining ENPP4 in Paraffin-embedded Human kidney tissue by Immunohistochemistry.

Anti-ENPP4 Antibody (aa171-200, APC) - LS-C246886 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENPP4 Antibody (aa171-200, Biotin) - LS-C246887 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENPP4 Antibody (aa171-200, AP) - LS-C234962 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENPP4 Antibody (aa171-200, FITC) - LS-C246888 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENPP4 Antibody (aa171-200, PE) - LS-C246889 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENPP4 Antibody - LS-C307919 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ENPP4 Antibody (aa171-200, Azide-free, HRP) - LS-C249911 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENPP4 Antibody (aa170-200) - LS-C321116 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENPP4 Antibody (aa171-200) - LS-C159532 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ENPP4 Antibody western blot of WiDr cell line lysates (35 ug/lane). The ENPP4 antibody detected the ENPP4 protein (arrow).

ENPP4 Antibody - NBP1-81466 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: ENPP4 Antibody [NBP1-81466] - Staining of human kidney shows cytoplasmic, membranous and nuclear positivity in renal tubules.

ENPP4 Antibody - H00022875-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ENPP4 Antibody [H00022875-B01] - analysis of ENPP4 expression in transfected 293T cell line by ENPP4 MaxPab polyclonal antibody. Lane 1: ENPP4 transfected lysate (49.83 KDa). Lane 2: Non-transfected lysate.

ENPP4 Antibody - H00022875-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ENPP4 antibody produced in rabbit - HPA016594 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ENPP4: <B>Cat. No. HPA016594</B>: Immunohistochemical staining of human kidney shows cytoplasmic, membranous and nuclear positivity in renal tubules.

Anti-ENPP4 antibody produced in mouse - SAB1407155 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ENPP4: <B>Cat. No. SAB1407155</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~49.8 kDa using ENPP4 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

ENPP4-Antibody-Center - AP18179c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ENPP4 Antibody (Center) (Cat. #AP18179c) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the ENPP4 antibody detected the ENPP4 protein (arrow).

ENPP4 Antibody - middle region (OAAB13673) - OAAB13673 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti -ENPP4 (Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 4, NPP4) - 210692 from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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