ENPP4

Gene Symbol ENPP4
Entrez Gene 22875
Alt Symbol NPP4
Species Human
Gene Type protein-coding
Description ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
Other Description AP3A hydrolase|AP3Aase|E-NPP 4|NPP-4|bis(5'-adenosyl)-triphosphatase ENPP4|ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)|ectonucleotide pyrophosphatase/phosphodiesterase family member 4
Swissprots Q9Y6X5 Q7L2N1 A8K5G1
Accessions CAJ78397 EAX04292 Q9Y6X5 AB020686 BAA74902 AJ420515 AK291276 BAF83965 BC018054 AAH18054 BI548305 CA433087 DA261977 DQ892332 ABM83258 DQ895537 ABM86463 NM_014936 NP_055751
Function Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors. {ECO:0000269|PubMed:22995898, ECO:0000269|PubMed:24338010}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22995898}; Single-pass type I membrane protein {ECO:0000269|PubMed:22995898}.
Tissue Specificity Expressed on the surface of vascular endothelia. {ECO:0000269|PubMed:22995898}.
Top Pathways Purine metabolism

Human ENPP4 full length protein - ab161455 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161455 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ENPP4 Antibody Blocking Peptide - LS-E5650 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ENPP4 Recombinant Protein - H00022875-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

ENPP4-Antibody-Center-Blocking-Peptide - BP18179c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

ENPP4 - H00022875-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

ENPP4 - H00022875-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

ENPP4 fusion protein - Ag11192 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human ENPP4, GST-tagged - ENPP4-12461H from Creative Biomart

Category Protein
Source E.coli
Species Human

ENPP4 Recombinant Protein Antigen - NBP1-81466PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Ectonucleotide pyrophosphatase/phosphodiesterase family member 4 (ENPP4), Recombinant Protein - MBS1414572 from MyBioSource

Category Protein
Prices $1,160.00, $1,160.00, $1,390.00, $1,390.00, $1,860.00, $1,860.00, $2,325.00, $2,325.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Orangutan
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