MST1R

Gene Symbol MST1R
Entrez Gene 4486
Alt Symbol CD136, CDw136, PTK8, RON
Species Human
Gene Type protein-coding
Description macrophage stimulating 1 receptor
Other Description MSP receptor|MST1R variant RON30|MST1R variant RON62|PTK8 protein tyrosine kinase 8|RON variant 21|RON variant E2E3|c-met-related tyrosine kinase|macrophage stimulating 1 receptor (c-met-related tyrosine kinase)|macrophage-stimulating protein receptor|p185-Ron|soluble RON variant 1|soluble RON variant 2|soluble RON variant 3|soluble RON variant 4
Swissprots B5A946 B5A945 B5A947 B5A944 Q04912
Accessions EAW65036 Q04912 AK303234 BAG64320 BP288515 BU542597 CA503122 EU826582 ACF47618 EU826583 ACF47619 EU826584 ACF47620 EU826585 ACF47621 HQ908652 AEB22138 JN689381 AEY68264 JN689382 AEY68265 JN983806 AEW68340 X70040 CAA49634 XM_005265170 XP_005265227 XM_011533739 XP_011532041 XM_011533740 XP_011532042 XM_011533741 XP_011532043 XM_011533742 XP_011532044 XM_011533743 XP_011532045 XM_011533744 XP_011532046 XM_011533745 XP_011532047 XR_245136 XR_940428 NM_001244937 NP_001231866 NM_002447 NP_002438
Function Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in respon
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in colon, skin, lung and bone marrow. {ECO:0000269|PubMed:8062829}.

PathScan ® Phospho-Ron (panTyr) Sandwich ELISA Kit - 12737 from Cell Signaling Technology

Category ELISA Kit
Prices $489.00
Sizes 1 kit (96 assays)

RON (CD136) Human ELISA Kit - ab174439 from Abcam

Category ELISA Kit
Sensitivity 0.46 ng/ml
Range 0.312 ng/ml - 20 ng/ml
Background-subtracted data values (mean +/- SD) are graphed.

Human Phospho-MSP R/Ron DuoSet IC ELISA - DYC1947-2 from R&D Systems

Category ELISA Kit
Prices $329.00, $649.00
Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates)

Human Phospho-MSP R/Ron DuoSet IC, 5 Plate - DYC1947-5 from R&D Systems

Category ELISA Kit

Human Total MSP R/Ron DuoSet IC ELISA - DYC691-2 from R&D Systems

Category ELISA Kit
Prices $329.00, $649.00
Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates)
Range 93.80 - 6,000 pg/mL

Human Total MSP R/Ron DuoSet IC, 5 Plate - DYC691-5 from R&D Systems

Category ELISA Kit

Custom Human MSP Receptor ELISA - ELH-MSPR from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

macrophage stimulating 1 receptor (c-met-related tyrosine kinase) , ELISA Kit - MBS9335511 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human MSP Receptor ELISA - RAB1585 from Sigma-Aldrich

Prices $615.00
Sizes 1 kt

Custom Human MSP Receptor ELISA - ELH-MSPR-1 from RayBiotech

Category ELISA Kit
Prices $627.00, $1,128.60, $2,508.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human MST1R ELISA Kit - E023416 from Biobool

Category ELISA Kit
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