IFITM2

Gene Symbol IFITM2
Entrez Gene 10581
Alt Symbol 1-8D, DSPA2c
Species Human
Gene Type protein-coding
Description interferon induced transmembrane protein 2
Other Description dispanin subfamily A member 2c|interferon-induced transmembrane protein 2|interferon-inducible protein 1-8D
Swissprots Q6FH82 Q01629 Q96DA8
Accessions CAK32181 EAW61220 EAW61221 Q01629 BC009696 AAH09696 BG164993 BG257141 BT009859 AAP88861 CR456894 CAG33175 CR541874 CAG46672 DQ891667 ABM82593 DQ894615 ABM85541 X02490 CAA26321 X57351 CAA40625 NM_006435 NP_006426
Function IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. {ECO:0000269|PubMed:19544527, ECO:0000269|PubMed:20064371, ECO:0000269|PubMed:20534863, ECO:0000269|PubMed:20943977, ECO:0000269|PubMed:21177806, ECO:0000269|PubMed:21253575, ECO:0000269|PubMed:22479637}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

IFITM2 Antibody - 13530 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from PANC-1 cells, human CD4+ T cells, and human CD8+ T cells using IFITM2 Antibody.

IFITM2 (A-6) - sc-373676 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IFITM2 (A-6): sc-373676. Western blot analysis of IFITM2 expression in non-transfected: sc-117752 (A) and mouse IFITM2 transfected: sc-126995 (B) 293T whole cell lysates.

IFITM2 (E-19) - sc-50902 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IFITM2 (E-19): sc-50902. Western blot analysis of IFITM2 expression in WEHI-231 whole cell lysate.

IFITM2/3 (N-14) - sc-131568 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-IFITM2 antibody - ab88415 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-IFITM2 antibody (ab88415) at 1 µg/ml + purified antigen at 0.2 µgSecondaryGoat Anti-Mouse IgG at 1/5000 dilution

Anti-IFITM2 antibody - ab68506 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-IFITM2 antibody (ab68506) at 1/500 dilution + human placenta lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-IFITM2 antibody - ab168617 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IFITM2 antibody (ab168617) at 1 µg/mlLane 1 : IFITM2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-IFITM2 antibody - N-terminal - ab175124 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-IFITM2 antibody - N-terminal (ab175124) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

Anti-IFITM2 Antibody (aa6-35, AP) - LS-C215210 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 Antibody (aa6-35, APC) - LS-C215211 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 Antibody (aa6-35, Biotin) - LS-C215212 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 Antibody (aa6-35, FITC) - LS-C215213 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 Antibody - LS-C308390 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-IFITM2 Antibody (aa6-35, Azide-free, HRP) - LS-C215214 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 Antibody (aa6-35, PE) - LS-C215215 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 Antibody - LS-C310704 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 Antibody (aa1-59) - LS-C308392 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-IFITM2 Antibody (aa6-35) - LS-C322156 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 Antibody (N-Terminus) - LS-C345446 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of IFM2 Antibody with human HeLa Whole Cell lysate.

Anti-IFITM2 Antibody (aa1-30) IHC-plus™ - LS-B9342 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-IFITM2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IFITM2 Antibody - H00010581-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: IFITM2 Antibody [H00010581-B01P] - Analysis of IFITM2 expression in human placenta.

IFITM2 Antibody - H00010581-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IFITM2 Antibody (1F2) - H00010581-M14 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F2
Western Blot: IFITM2 Antibody (1F2) [H00010581-M14] - Analysis of IFITM2 expression in HepG2 (Cat # L019V1).

IFITM2 Polyclonal Antibody - bs-15517R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-IFITM2 antibody produced in mouse - SAB1400394 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-IFITM2, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400394</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~14.5 kDa using human placenta lysate.
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