IFITM2

Gene Symbol	IFITM2
Entrez Gene	10581
Alt Symbol	1-8D, DSPA2c
Species	Human
Gene Type	protein-coding
Description	interferon induced transmembrane protein 2
Other Description	dispanin subfamily A member 2c|interferon-induced transmembrane protein 2|interferon-inducible protein 1-8D
Swissprots	Q6FH82 Q01629 Q96DA8
Accessions	CAK32181 EAW61220 EAW61221 Q01629 BC009696 AAH09696 BG164993 BG257141 BT009859 AAP88861 CR456894 CAG33175 CR541874 CAG46672 DQ891667 ABM82593 DQ894615 ABM85541 X02490 CAA26321 X57351 CAA40625 NM_006435 NP_006426
Function	IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. {ECO:0000269|PubMed:19544527, ECO:0000269|PubMed:20064371, ECO:0000269|PubMed:20534863, ECO:0000269|PubMed:20943977, ECO:0000269|PubMed:21177806, ECO:0000269|PubMed:21253575, ECO:0000269|PubMed:22479637}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IFITM2-Over-expression-Lysate - LY13874a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

IFITM2 293T Cell Transient Overexpression Lysate(Denatured) - H00010581-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

IFITM2 overexpression lysate - LY401937 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

IFITM2 293 Cell Lysate - 401725 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

IFITM2 Overexpression Lysate (Denatured) - H00010581-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

IFITM2 Overexpression Lysate (Native) - NBL1-11840 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

IFITM2 Over-expression Lysate Product - GWB-58E45E from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human IFITM2 Knockdown Stable Cell Line - CSC-DC007432 from Creative biogene Category Cell Line Species Human

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