IFITM2

Gene Symbol	IFITM2
Entrez Gene	10581
Alt Symbol	1-8D, DSPA2c
Species	Human
Gene Type	protein-coding
Description	interferon induced transmembrane protein 2
Other Description	dispanin subfamily A member 2c|interferon-induced transmembrane protein 2|interferon-inducible protein 1-8D
Swissprots	Q6FH82 Q01629 Q96DA8
Accessions	CAK32181 EAW61220 EAW61221 Q01629 BC009696 AAH09696 BG164993 BG257141 BT009859 AAP88861 CR456894 CAG33175 CR541874 CAG46672 DQ891667 ABM82593 DQ894615 ABM85541 X02490 CAA26321 X57351 CAA40625 NM_006435 NP_006426
Function	IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. {ECO:0000269|PubMed:19544527, ECO:0000269|PubMed:20064371, ECO:0000269|PubMed:20534863, ECO:0000269|PubMed:20943977, ECO:0000269|PubMed:21177806, ECO:0000269|PubMed:21253575, ECO:0000269|PubMed:22479637}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IFITM2 full length protein - ab92922 from Abcam Category Protein Source E. coli Species Human

IFITM2 Antibody Blocking Peptide - LS-E7579 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IFITM2 Protein - H00010581-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human IFITM2 Protein - H00010581-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IFITM2 Partial Recombinant Protein - H00010581-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IFM2-Antibody-N-term-Blocking-Peptide - BP4767a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IFITM2 - H00010581-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

IFITM2 - H00010581-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

IFITM2 - H00010581-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

IFITM2 - H00010581-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

IFITM2 - H00010581-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

IFITM2 - H00010581-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

IFITM2 (1-132) - PRO-50010-0010 from Acris Antibodies Category Protein Prices $205.00 Sizes 10 µg Source E. coli Species Human

IFITM2 (1-132) - PRO-50010-0025 from Acris Antibodies Category Protein Prices $255.00 Sizes 25 µg Source E. coli Species Human

IFITM2 (1-132) - PRO-50010-0050 from Acris Antibodies Category Protein Prices $390.00 Sizes 50 µg Source E. coli Species Human

IFITM2 fusion protein - Ag3451 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

IFITM2 fusion protein - Ag17917 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human IFITM2, GST-His - IFITM2-2933H from Creative Biomart Category Protein Source E.coli.

Recombinant Human IFITM2, His-tagged - IFITM2-29419TH from Creative Biomart Category Protein Source E. coli

Recombinant Human IFITM2, GST-tagged - IFITM2-14072H from Creative Biomart Category Protein Source E.coli Species Human

IFITM2 Blocking Peptide - abx061953 from Abbexa Category Peptide

IFITM2 Peptide, Human - M34GP07432H from Creative Peptides Category Peptide Source Synthetic. Species Human

IFITM2 Blocking Peptide - CBP7343 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Interferon-induced transmembrane protein 2 (IFITM2), Recombinant Protein - MBS959351 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Interferon-induced transmembrane protein 2 (IFITM2), Recombinant Protein - MBS7017424 from MyBioSource Category Protein Prices $960.00, $1,940.00, $3,150.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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