IFITM2

Gene Symbol IFITM2
Entrez Gene 10581
Alt Symbol 1-8D, DSPA2c
Species Human
Gene Type protein-coding
Description interferon induced transmembrane protein 2
Other Description dispanin subfamily A member 2c|interferon-induced transmembrane protein 2|interferon-inducible protein 1-8D
Swissprots Q6FH82 Q01629 Q96DA8
Accessions CAK32181 EAW61220 EAW61221 Q01629 BC009696 AAH09696 BG164993 BG257141 BT009859 AAP88861 CR456894 CAG33175 CR541874 CAG46672 DQ891667 ABM82593 DQ894615 ABM85541 X02490 CAA26321 X57351 CAA40625 NM_006435 NP_006426
Function IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. {ECO:0000269|PubMed:19544527, ECO:0000269|PubMed:20064371, ECO:0000269|PubMed:20534863, ECO:0000269|PubMed:20943977, ECO:0000269|PubMed:21177806, ECO:0000269|PubMed:21253575, ECO:0000269|PubMed:22479637}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

IFITM2 CRISPR/Cas9 KO Plasmid (h) - sc-403889 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM2 HDR Plasmid (h) - sc-403889-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM2 Double Nickase Plasmid (h) - sc-403889-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM2 Double Nickase Plasmid (h2) - sc-403889-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM2 CRISPR Activation Plasmid (h) - sc-403889-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM2 CRISPR Activation Plasmid (h2) - sc-403889-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM2 Lentiviral Activation Particles (h) - sc-403889-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM2 Lentiviral Activation Particles (h2) - sc-403889-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM2 siRNA (h) - sc-96760 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IFITM2 shRNA Plasmid (h) - sc-96760-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IFITM2 shRNA (h) Lentiviral Particles - sc-96760-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU109931 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10471 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10471 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01607 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01607

IFITM2 siRNA (Human) - CRH7201 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IFITM2 - MBS8230773 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IFITM2 (NM_006435.2) - SHH316961 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human IFITM2(NM_006435.2) - SHL166260 from Creative biogene

Category siRNA
Species Reactivities Human

Human IFITM2 siRNA - orb267703 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IFITM2 shRNA Plasmid (Human) - CHH7201 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IFITM2 miRNA 3'UTR clone - MiUTR1H-04807 from Creative biogene

Species Reactivities Human
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