IFITM2

Gene Symbol IFITM2
Entrez Gene 10581
Alt Symbol 1-8D, DSPA2c
Species Human
Gene Type protein-coding
Description interferon induced transmembrane protein 2
Other Description dispanin subfamily A member 2c|interferon-induced transmembrane protein 2|interferon-inducible protein 1-8D
Swissprots Q6FH82 Q01629 Q96DA8
Accessions CAK32181 EAW61220 EAW61221 Q01629 BC009696 AAH09696 BG164993 BG257141 BT009859 AAP88861 CR456894 CAG33175 CR541874 CAG46672 DQ891667 ABM82593 DQ894615 ABM85541 X02490 CAA26321 X57351 CAA40625 NM_006435 NP_006426
Function IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. {ECO:0000269|PubMed:19544527, ECO:0000269|PubMed:20064371, ECO:0000269|PubMed:20534863, ECO:0000269|PubMed:20943977, ECO:0000269|PubMed:21177806, ECO:0000269|PubMed:21253575, ECO:0000269|PubMed:22479637}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Human-IFITM2-cDNA-Clone - DC02727 from Abgent, a WuXi AppTec company

Prices $178.20
Sizes 10 µg
Species Human
Accession BC009696

IFITM2 - MBS1268804 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC009696

Human IFITM2 ORF Clone(NM_006435.2) - CDCL166832 from Creative Biomart

Species Human
Accession NM_006435.2

Human IFITM2 ORF Clone (BC009696) - CDCS412738 from Creative biogene

Species Human
Accession Q01629
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