Gene Symbol | MIXL1 |
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Entrez Gene | 83881 |
Alt Symbol | MILD1, MIX, MIXL |
Species | Human |
Gene Type | protein-coding |
Description | Mix paired-like homeobox |
Other Description | MIX1 homeobox-like protein 1|Mix-like homeobox protein 1|homeobox protein MIXL1|homeodomain protein MIX|mix.1 homeobox-like protein |
Swissprots | B7ZLF9 Q9H2W2 |
Accessions | AAK01479 EAW69778 EAW69779 Q9H2W2 AF211891 AAG35776 BC111974 AAI11975 BC113441 AAI13442 BC143784 AAI43785 CX165667 XM_011544287 XP_011542589 NM_001282402 NP_001269331 NM_031944 NP_114150 |
Function | Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12070013, ECO:0000269|PubMed:17303500}. |
Tissue Specificity | Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level). {ECO:0000269|PubMed:12070013, ECO:0000269|PubMed:16433620, ECO:0000269|PubMed:17303500}. |
MIXL1 (A-8) - sc-390976 from Santa Cruz Biotechnology
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MIXL1 (H-50) - sc-98664 from Santa Cruz Biotechnology
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MIXL1 (K-18) - sc-104376 from Santa Cruz Biotechnology
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MIXL1 (S-14) - sc-104378 from Santa Cruz Biotechnology
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Anti-Mixl1 antibody - ab188654 from Abcam
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Anti-Mixl1 antibody - ab28411 from Abcam
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Anti-Mixl1 antibody - ab139146 from Abcam
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Anti-Mixl1 antibody - ab57854 from Abcam
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Anti-MIXL1 / MIXL Antibody (aa122-151, AP) - LS-C237667 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (aa122-151, Biotin) - LS-C237668 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (aa122-151, APC) - LS-C237669 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (aa122-151, FITC) - LS-C237670 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (aa122-151, PE) - LS-C246507 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (aa86-186) - LS-C309007 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (aa122-151) - LS-C323013 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (aa122-151, Azide-free, HRP) - LS-C248823 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (N-Terminus) - LS-C30095 from LifeSpan Bioscience
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Anti-MIXL1 / MIXL Antibody (aa122-151) - LS-C158144 from LifeSpan Bioscience
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MIXL1 Antibody (319919) - MAB2610 from Novus Biologicals
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MIXL1 Antibody (4D11) - H00083881-M02 from Novus Biologicals
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MIXL1 Polyclonal Antibody - bs-12350R from Bioss
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MIXL1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12350R-A350 from Bioss
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MIXL1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12350R-A488 from Bioss
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MIXL1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12350R-A555 from Bioss
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MIXL1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12350R-A647 from Bioss
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