MIXL1

Gene Symbol MIXL1
Entrez Gene 83881
Alt Symbol MILD1, MIX, MIXL
Species Human
Gene Type protein-coding
Description Mix paired-like homeobox
Other Description MIX1 homeobox-like protein 1|Mix-like homeobox protein 1|homeobox protein MIXL1|homeodomain protein MIX|mix.1 homeobox-like protein
Swissprots B7ZLF9 Q9H2W2
Accessions AAK01479 EAW69778 EAW69779 Q9H2W2 AF211891 AAG35776 BC111974 AAI11975 BC113441 AAI13442 BC143784 AAI43785 CX165667 XM_011544287 XP_011542589 NM_001282402 NP_001269331 NM_031944 NP_114150
Function Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12070013, ECO:0000269|PubMed:17303500}.
Tissue Specificity Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level). {ECO:0000269|PubMed:12070013, ECO:0000269|PubMed:16433620, ECO:0000269|PubMed:17303500}.

MIXL1 CRISPR/Cas9 KO Plasmid (h) - sc-405367 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MIXL1 HDR Plasmid (h) - sc-405367-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MIXL1 Double Nickase Plasmid (h) - sc-405367-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MIXL1 Double Nickase Plasmid (h2) - sc-405367-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MIXL1 CRISPR Activation Plasmid (h) - sc-405367-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MIXL1 CRISPR Activation Plasmid (h2) - sc-405367-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MIXL1 Lentiviral Activation Particles (h) - sc-405367-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MIXL1 Lentiviral Activation Particles (h2) - sc-405367-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MIXL1 siRNA (h) - sc-88374 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MIXL1 shRNA Plasmid (h) - sc-88374-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MIXL1 shRNA (h) Lentiviral Particles - sc-88374-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MIXL1 RNAi - H00083881-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU049121 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14374 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14374 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MIXL1 siRNA (Human) - CRJ3221 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MIXL1(NM_031944.1) - SHH190847 from Creative biogene

Category siRNA
Species Reactivities Human

Human MIXL1 siRNA - orb273722 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MIXL1 shRNA Plasmid (Human) - CHJ3221 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MIXL1 miRNA 3'UTR clone - MiUTR1H-06311 from Creative biogene

Species Reactivities Human
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