Gene Symbol | MIXL1 |
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Entrez Gene | 83881 |
Alt Symbol | MILD1, MIX, MIXL |
Species | Human |
Gene Type | protein-coding |
Description | Mix paired-like homeobox |
Other Description | MIX1 homeobox-like protein 1|Mix-like homeobox protein 1|homeobox protein MIXL1|homeodomain protein MIX|mix.1 homeobox-like protein |
Swissprots | B7ZLF9 Q9H2W2 |
Accessions | AAK01479 EAW69778 EAW69779 Q9H2W2 AF211891 AAG35776 BC111974 AAI11975 BC113441 AAI13442 BC143784 AAI43785 CX165667 XM_011544287 XP_011542589 NM_001282402 NP_001269331 NM_031944 NP_114150 |
Function | Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12070013, ECO:0000269|PubMed:17303500}. |
Tissue Specificity | Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level). {ECO:0000269|PubMed:12070013, ECO:0000269|PubMed:16433620, ECO:0000269|PubMed:17303500}. |
Human Mixl1 peptide - ab30617 from Abcam
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Human Mixl1 protein fragment - ab153546 from Abcam
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MIXL1 / MIXL Antibody Blocking Peptide - LS-E6516 from LifeSpan Bioscience
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MIXL1 / MIXL Antibody Blocking Peptide - LS-E10470 from LifeSpan Bioscience
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Recombinant Human MIXL1 Protein - H00083881-Q01 from Novus Biologicals
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MIXL1-Antibody-Center-Blocking-Peptide - BP19284c from Abgent, a WuXi AppTec company
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MIXL1 - H00083881-Q01-10 from Acris Antibodies
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MIXL1 - H00083881-Q01-25 from Acris Antibodies
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MIXL1 fusion protein - ag18732 from Proteintech Group
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Recombinant Human Homeobox protein MIXL1(MIXL1) - CSB-YP887966HU CSB-EP887966HU CSB-BP887966HU CSB-MP887966HU from Cusabio
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MIXL1-Blocking-Peptide-C-term - BP21011c from Abgent, a WuXi AppTec company
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MIXL1 Peptide, Human - M34GP09539H from Creative Peptides
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MIXL1 Recombinant Protein Antigen - NBP2-55175PEP from Novus Biologicals
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Homeobox protein MIXL1 (MIXL1), Recombinant Protein - MBS1486029 from MyBioSource
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