FIGLA

Gene Symbol FIGLA
Entrez Gene 344018
Alt Symbol BHLHC8, FIGALPHA, POF6
Species Human
Gene Type protein-coding
Description folliculogenesis specific basic helix-loop-helix
Other Description class C basic helix-loop-helix protein 8|factor in the germline alpha|folliculogenesis-specific basic helix-loop-helix protein|transcription factor FIGa
Swissprots Q6QHK4
Accessions EAW99795 EAW99796 EAW99797 Q6QHK4 AY541030 AAS48452 BC039536 BC146287 AAI46288 BC148798 AAI48799 NM_001004311 NP_001004311
Function Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E- box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters. {ECO:0000269|PubMed:15044608}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Germ cells. Expressed in the fetal ovary, but not by a range of other tissues. Expression increases across mid- gestation, rising some 40-fold by the time of primordial follicle formation. {ECO:0000269|PubMed:12468641, ECO:0000269|PubMed:15044608}.

FIGLA (E-12) - sc-161048 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FIGLA (H-103) - sc-367364 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-FIGLA antibody - ab173725 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FIGLA antibody (ab173725) at 1/100 dilution + T47D cell line lysate at 35 µgdeveloped using the ECL technique

Anti-FIGLA antibody - ab169418 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-FIGLA antibody (ab169418) at 1 µg/mlLane 1 : FIGLA transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-FIGLA antibody - C-terminal - ab170973 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-FIGLA antibody - C-terminal (ab170973) at 1 µg/ml + Mouse spleen lysate at 10 µg

Anti-FIGLA Antibody (aa108-137, AP) - LS-C257289 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGLA Antibody (aa108-137, APC) - LS-C257291 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGLA Antibody (aa108-137, Biotin) - LS-C257292 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGLA Antibody (aa108-137, FITC) - LS-C257293 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGLA Antibody (aa108-137, Azide-free, HRP) - LS-C259386 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGLA Antibody (aa108-137, PE) - LS-C259387 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGLA Antibody (aa107-137) - LS-C321391 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGLA Antibody (C-Terminus) - LS-C170151 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-FIGLA Antibody (aa108-137) - LS-C159658 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FIGLA Antibody western blot of T47D cell line lysates (35 ug/lane). The FIGLA antibody detected the FIGLA protein (arrow).

FIGLA Antibody (6A10) - H00344018-M03-100ug from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6A10

FIGLA Antibody - H00344018-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

ANTI-FIGLA (CENTER) antibody produced in rabbit - SAB1301946 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-FIGLA (Center): <B>Cat. No. SAB1301946</B>: FIGLA Antibody (Center) western blot analysis in T47D cell line lysates (35 μg/lane).

Anti-FIGLA antibody produced in mouse - SAB1411730 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-FIGLA: <B>Cat. No. SAB1411730</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~24.1 kDa using FIGLA transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-FIGLA antibody produced in mouse - SAB1412955 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6A10
<B>Immunoblotting</B><BR/>Anti-FIGLA:<B>Cat. No. SAB1412955</B>: Antibody concentration: 1 μg/mL. Immunofluorescence band of ~37.8 kDa using immunogen protein lysate.

FIGLA-Antibody-Center - AP18020c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FIGLA Antibody (Center) at 1:1000 dilution Lane 1: human ovary lysate Lane 2: T47D whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 24 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

FIGLA Antibody - middle region (OAAB13459) - OAAB13459 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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