FIGLA

Gene Symbol	FIGLA
Entrez Gene	344018
Alt Symbol	BHLHC8, FIGALPHA, POF6
Species	Human
Gene Type	protein-coding
Description	folliculogenesis specific basic helix-loop-helix
Other Description	class C basic helix-loop-helix protein 8|factor in the germline alpha|folliculogenesis-specific basic helix-loop-helix protein|transcription factor FIGa
Swissprots	Q6QHK4
Accessions	EAW99795 EAW99796 EAW99797 Q6QHK4 AY541030 AAS48452 BC039536 BC146287 AAI46288 BC148798 AAI48799 NM_001004311 NP_001004311
Function	Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E- box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters. {ECO:0000269|PubMed:15044608}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Germ cells. Expressed in the fetal ovary, but not by a range of other tissues. Expression increases across mid- gestation, rising some 40-fold by the time of primordial follicle formation. {ECO:0000269|PubMed:12468641, ECO:0000269|PubMed:15044608}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FIGLA full length protein - ab166309 from Abcam Category Protein Source Wheat germ Species Human

Human FIGLA protein fragment - ab166310 from Abcam Category Protein Source Wheat germ Species Human

FIGLA Antibody Blocking Peptide - LS-E5500 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FIGLA Antibody Blocking Peptide - LS-E13330 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FIGLA Protein - H00344018-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

FIGLA Partial Recombinant Protein - H00344018-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

FIGLA-Antibody-Center-Blocking-Peptide - BP18020c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FIGLA - H00344018-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

FIGLA - H00344018-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FIGLA - H00344018-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FIGLA fusion protein - ag20392 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

FIGLA fusion protein - ag20206 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human FIGLA - FIGLA-899H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Factor in the germline alpha(FIGLA) - CSB-YP750909HU CSB-EP750909HU CSB-BP750909HU CSB-MP750909HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FIGLA - TP312562 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

FIGLA Peptide, Human - M34GP05746H from Creative Peptides Category Peptide Source Synthetic. Species Human

Factor in the germline alpha (FIGLA), Recombinant Protein - MBS1488108 from MyBioSource Category Protein Prices $970.00, $970.00, $1,195.00, $1,195.00, $1,460.00, $1,460.00, $1,925.00, $1,925.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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