HR

Gene Symbol HR
Entrez Gene 55806
Alt Symbol ALUNC, AU, HSA277165, HYPT4, MUHH, MUHH1
Species Human
Gene Type protein-coding
Description hair growth associated
Other Description hairless homolog|lysine-specific demethylase hairless|protein hairless
Swissprots Q6GS30 Q9NPE1 Q96H33 O43593
Accessions AIW82258 AIW82259 AIW82260 AIW82261 AIW82262 EAW63716 EAW63717 EAW63718 O43593 AF039196 AAC32258 AJ277165 CAB86602 AK098053 AK308839 AL833253 AW291630 BC008946 BC067128 AAH67128 BM982749 BX109092 DA114279 DA326731 XM_005273569 XP_005273626 XM_006716367 XP_006716430 NM_005144 NP_005135 NM_018411 NP_060881
Function Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (via targeting of collagens), neural activity, and cell cycle. {ECO:0000269|PubMed:24334705}.
Subcellular Location Nucleus.
Tissue Specificity Strongest expression of isoforms 1 and 2 is seen in the small intestine, weaker expression in brain and colon, and trace expression is found in liver, pancreas, spleen, thymus, stomach, salivary gland, appendix and trachea. Isoform 1 is always the most abundant. Isoform 1 is exclusively expressed at low levels in kidney and testis. Isoform 2 is exclusively expressed at high levels in the skin. {ECO:0000269|PubMed:10051399, ECO:0000269|PubMed:9736769}.

HR overexpression lysate - LY413066 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

HR overexpression lysate - LY417487 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

Hairless Overexpression Lysate (Native) - NBP2-06803 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: Hairless Overexpression Lysate (Adult Normal) [NBP2-06803] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Hairless.

HR (h): 293T Lysate - sc-116984 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

Hairless Overexpression Lysate (Native) - NBP2-11591 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Hairless Overexpression Lysate (Adult Normal) [NBP2-11591] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Hairless.

HR-knockout Cell lysate - LC810371 from Acris Antibodies

Category Cell Lysate
Prices $495.00
Sizes 100 µg

Panoply™ Human HR Knockdown Stable Cell Line - CSC-DC007241 from Creative biogene

Category Cell Line
Species Human

Human HR Knockout Cell Line-HeLa - CSC-RT0631 from Creative biogene

Category Cell Line
Species Human

HR KO Cell Lysate-HeLa - CLKO-0137 from Creative biogene

Category Cell Lysate
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