C1D

Gene Symbol	C1D
Entrez Gene	10438
Alt Symbol	LRP1, Rrp47, SUN-CoR, SUNCOR, hC1D
Species	Human
Gene Type	protein-coding
Description	C1D nuclear receptor corepressor
Other Description	C1D DNA-binding protein|C1D nuclear receptor co-repressor|nuclear DNA-binding protein|nuclear nucleic acid-binding protein C1D|small unique nuclear receptor co-repressor|small unique nuclear receptor corepressor
Swissprots	Q05D64 Q13901 D6W5F8 A8K336
Accessions	AAX88887 EAW99884 EAW99885 EAW99886 Q13901 AI004680 AK290451 BAF83140 BC005235 AAH05235 BC009584 AAH09584 BC009589 AAH09589 BC016284 AAH16284 BG505686 BM354091 CN342947 DA900336 EU446867 ABZ92396 X95592 CAA64845 NM_001190263 NP_001177192 NM_001190265 NP_001177194 NM_006333 NP_006324 NM_173177 NP_775269
Function	Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Nucleus, nucleolus. Note=EXOSC10 is required for nucleolar localization.
Tissue Specificity	Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung and colon. {ECO:0000269|PubMed:10362552}.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

C1D-Over-expression-Lysate - LY13881a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

C1D 293T Cell Transient Overexpression Lysate(Denatured) - H00010438-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

C1D overexpression lysate - LY416720 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

C1D 293 Cell Lysate - 407810 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

C1D 293 Cell Lysate - 403989 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

C1D Overexpression Lysate (Native) - NBL1-08284 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

C1D Overexpression Lysate (Native) - NBL1-08285 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

C1D Over-expression Lysate Product - GWB-6744AC from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

C1D Over-expression Lysate Product - GWB-461FBD from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human LRP1 / A2MR / CD91 (aa 786-1165) HEK293 Cell Lysate (WB positive control) - 11665-HCCHL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

C1D Overexpression Lysate (Denatured) - H00010438-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Human LRP1 Human Cells Transfected Lysate (positive control) (denatured) - orb175497 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human C1D Knockdown Stable Cell Line - CSC-DC001851 from Creative biogene Category Cell Line Species Human

C1D Knockout Cell Line-HeLa - CSC-RT1764 from Creative biogene Category Cell Line Species Human

C1D KO Cell Lysate-HeLa - CLKO-1610 from Creative biogene Category Cell Lysate

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