C1D

Gene Symbol	C1D
Entrez Gene	10438
Alt Symbol	LRP1, Rrp47, SUN-CoR, SUNCOR, hC1D
Species	Human
Gene Type	protein-coding
Description	C1D nuclear receptor corepressor
Other Description	C1D DNA-binding protein|C1D nuclear receptor co-repressor|nuclear DNA-binding protein|nuclear nucleic acid-binding protein C1D|small unique nuclear receptor co-repressor|small unique nuclear receptor corepressor
Swissprots	Q05D64 Q13901 D6W5F8 A8K336
Accessions	AAX88887 EAW99884 EAW99885 EAW99886 Q13901 AI004680 AK290451 BAF83140 BC005235 AAH05235 BC009584 AAH09584 BC009589 AAH09589 BC016284 AAH16284 BG505686 BM354091 CN342947 DA900336 EU446867 ABZ92396 X95592 CAA64845 NM_001190263 NP_001177192 NM_001190265 NP_001177194 NM_006333 NP_006324 NM_173177 NP_775269
Function	Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Nucleus, nucleolus. Note=EXOSC10 is required for nucleolar localization.
Tissue Specificity	Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung and colon. {ECO:0000269|PubMed:10362552}.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human C1D full length protein - ab156979 from Abcam Category Protein Prices $345.00 Sizes 50 µg Source E. coli Species Human

Human C1D full length protein - ab160994 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Human C1D full length protein - ab160995 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human C1D protein fragment - ab160996 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

C1D Antibody Blocking Peptide - LS-E18242 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

C1D Antibody Blocking Peptide - LS-E18243 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

C1D Antibody Blocking Peptide - LS-E26931 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LRP1 / CD91 Antibody Blocking Peptide - LS-E7282 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LRP1 / CD91 Antibody Blocking Peptide - LS-E21430 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LRP1 / CD91 Antibody Blocking Peptide - LS-E21431 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

C1D Partial Recombinant Protein - H00010438-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

C1D Recombinant Protein - H00010438-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Low Density LRP Protein - H00004035-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

C1D Recombinant Protein - H00010438-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human C1D Protein - NBP2-22721 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

Intermediate Density Lipoproteins Native Protein - NBP1-99539 from Novus Biologicals Category Protein Prices $225.00 Sizes 1 mg Source Human Species Human

Recombinant Human Low Density LRP Protein - H00004035-G01 from Novus Biologicals Category Protein Prices $519.00 Sizes 2 µg Source Wheat Germ Species Human

Low Density LRP Peptide - P1342 from Novus Biologicals Category Peptide Species Human

C1D-Antibody-N-term-Blocking-Peptide - BP19594a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

C1D blocking peptide - GTX88500-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Human C1D protein - orb245178 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human C1D protein - orb191242 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli Species Human

Human C1D protein (GST Tag) - orb138284 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

C1D Blocking Peptide - 33R-1192 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

C1D Blocking Peptide - 33R-4854 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

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