C1D

Gene Symbol C1D
Entrez Gene 10438
Alt Symbol LRP1, Rrp47, SUN-CoR, SUNCOR, hC1D
Species Human
Gene Type protein-coding
Description C1D nuclear receptor corepressor
Other Description C1D DNA-binding protein|C1D nuclear receptor co-repressor|nuclear DNA-binding protein|nuclear nucleic acid-binding protein C1D|small unique nuclear receptor co-repressor|small unique nuclear receptor corepressor
Swissprots Q05D64 Q13901 D6W5F8 A8K336
Accessions AAX88887 EAW99884 EAW99885 EAW99886 Q13901 AI004680 AK290451 BAF83140 BC005235 AAH05235 BC009584 AAH09584 BC009589 AAH09589 BC016284 AAH16284 BG505686 BM354091 CN342947 DA900336 EU446867 ABZ92396 X95592 CAA64845 NM_001190263 NP_001177192 NM_001190265 NP_001177194 NM_006333 NP_006324 NM_173177 NP_775269
Function Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus, nucleolus. Note=EXOSC10 is required for nucleolar localization.
Tissue Specificity Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung and colon. {ECO:0000269|PubMed:10362552}.
Top Pathways RNA degradation

C1D CRISPR/Cas9 KO Plasmid (h) - sc-417563 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1D HDR Plasmid (h) - sc-417563-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1D Double Nickase Plasmid (h) - sc-417563-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1D Double Nickase Plasmid (h2) - sc-417563-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1D CRISPR Activation Plasmid (h) - sc-417563-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1D CRISPR Activation Plasmid (h2) - sc-417563-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1D Lentiviral Activation Particles (h) - sc-417563-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1D Lentiviral Activation Particles (h2) - sc-417563-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1D siRNA (h) - sc-94710 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C1D shRNA Plasmid (h) - sc-94710-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C1D shRNA (h) Lentiviral Particles - sc-94710-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C1D RNAi - H00010438-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

C1D RNAi - H00010438-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU073061 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4566 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4566 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05758 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05758

C1D siRNA (Human) - CRH7080 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

C1D - MBS8224680 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

C1D shRNA Plasmid (Human) - CHH7080 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C1D miRNA 3'UTR clone - MiUTR3H-08887 from Creative biogene

Species Reactivities Human

C1D miRNA 3'UTR clone - MiUTR3H-08888 from Creative biogene

Species Reactivities Human
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