C1D

Gene Symbol C1D
Entrez Gene 10438
Alt Symbol LRP1, Rrp47, SUN-CoR, SUNCOR, hC1D
Species Human
Gene Type protein-coding
Description C1D nuclear receptor corepressor
Other Description C1D DNA-binding protein|C1D nuclear receptor co-repressor|nuclear DNA-binding protein|nuclear nucleic acid-binding protein C1D|small unique nuclear receptor co-repressor|small unique nuclear receptor corepressor
Swissprots Q05D64 Q13901 D6W5F8 A8K336
Accessions AAX88887 EAW99884 EAW99885 EAW99886 Q13901 AI004680 AK290451 BAF83140 BC005235 AAH05235 BC009584 AAH09584 BC009589 AAH09589 BC016284 AAH16284 BG505686 BM354091 CN342947 DA900336 EU446867 ABZ92396 X95592 CAA64845 NM_001190263 NP_001177192 NM_001190265 NP_001177194 NM_006333 NP_006324 NM_173177 NP_775269
Function Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus, nucleolus. Note=EXOSC10 is required for nucleolar localization.
Tissue Specificity Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung and colon. {ECO:0000269|PubMed:10362552}.
Top Pathways RNA degradation

Anti-C1D antibody - ab80497 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-C1D antibody (ab80497) at 0.1 µg/ml + human skeletal muscle lysate (in RIPA buffer) at 35 µg

Anti-C1D antibody - ab58320 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-C1D antibody [EPR11122] - ab166897 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11122
All lanes : Anti-C1D antibody [EPR11122] (ab166897) at 1/1000 dilutionLane 1 : Human fetal heart lysateLane 2 : Human skeletal muscle lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP antibody at 1/2000 dilution

Anti-C1D Antibody (FITC) - LS-C211846 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C1D Antibody (Biotin) - LS-C211847 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C1D Antibody (aa47-96) - LS-C81569 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.

Anti-C1D Antibody (N-Terminus) - LS-C81568 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.

Anti-C1D Antibody (aa127-141) - LS-C87383 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.1 ug/ml) staining of Human Skeletal Muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

Anti-C1D Antibody - LS-C334727 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HeLa cell using C1D antibody. Blue: DAPI for nuclear staining.

Anti-C1D Antibody (clone 6H2) - LS-C133645 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6H2
Immunofluorescence of monoclonal antibody to C1D on HeLa cell. [antibody concentration 10 ug/ml]

Anti-C1D Antibody (HRP) - LS-C211845 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C1D Antibody (aa1-135) IHC-plus™ - LS-B12252 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

C1D Antibody (6H2) - H00010438-M03 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6H2
Western Blot: C1D Antibody (6H2) [H00010438-M03] - Analysis of C1D expression in HeLa (Cat # L013V1).

C1D Antibody - AF4816 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of JEG‑3 human epithelial choriocarcinoma cell line. PVDF membrane was probed with 2 µg/mL of Goat Anti-Human C1D Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4816) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for C1D at approximately 16 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

C1D Antibody - NBP1-79373 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: C1D Antibody [NBP1-79373] - Human Heart lysate, concentration 0.2-1 ug/ml.

C1D Antibody - NBP1-79372 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C1D Antibody [NBP1-79372] - Hela cell lysate, concentration 0.2-1 ug/ml.

C1D Antibody - NBP1-81287 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: C1D Antibody [NBP1-81287] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

C1D Antibody - H00010438-B01 from Novus Biologicals

Host Mouse
Clonality Polyclonal
Western Blot: C1D Antibody [H00010438-B01] - analysis of C1D expression in transfected 293T cell line by C1D MaxPab polyclonal antibody (B01). Lane 1: C1D transfected lysate (16.00 KDa). Lane 2: Non-transfected lysate.

C1D Antibody - NBP1-06982 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

C1D Antibody - NBP2-15639 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C1D Antibody [NBP2-15639] - Sample (30 ug of whole cell lysate) A: Raji 15% SDS PAGE gel, diluted at 1:1000.

C1D Antibody (6H2) - H00010438-M03A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 6H2
Western Blot: C1D Antibody (6H2) [H00010438-M03A] - C1D monoclonal antibody (M03), clone 6H2 Western Blot analysis of C1D expression in HeLa ( Cat # L013V1 ).

C1D Antibody (4H5) - H00010438-M10 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4H5
Western Blot: C1D Antibody (4H5) [H00010438-M10] - Analysis of C1D expression in transfected 293T cell line by C1D monoclonal antibody (M10), clone 4H5. Lane 1: C1D transfected lysatE (16 KDa). Lane 2: Non-transfected lysate.

C1D Antibody - H00010438-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-C1D (AB1) antibody produced in rabbit - AV50533 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HeLa (<B>Cat. No. AV50533</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type HeLa

Anti-C1D (AB2) antibody produced in rabbit - AV50534 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: fetal heart (<B>Cat. No. AV50534</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type fetal heart
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