CLDN16

Gene Symbol	CLDN16
Entrez Gene	10686
Alt Symbol	HOMG3, PCLN1
Species	Human
Gene Type	protein-coding
Description	claudin 16
Other Description	PCLN-1|claudin-16|hypomagnesemia 3, with hypercalciuria and nephrocalcinosis|paracellin-1
Swissprots	Q9Y5I7
Accessions	EAW78106 Q9Y5I7 AF152101 AAD43096 AK314955 BC069662 AAH69662 BC069682 AAH69682 BC069759 AAH69759 BC069777 AAH69777 BF034334 CB241927 DQ305102 ABC47832 HQ448426 ADQ32906 NM_006580 NP_006571
Function	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.
Subcellular Location	Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Kidney-specific, including the thick ascending limb of Henle (TAL).
Top Pathways	Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat CLDN16 / Claudin 16 ELISA Kit (Sandwich ELISA) - LS-F9846 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.53 ng/ml Range 1.56-100 ng/ml

Claudin-16 (CLDN16), Human, ELISA Kit - E01C0979 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/ml

Claudin 16 (CLDN16), ELISA Kit - MBS2021132 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.53ng/mL. Range 1.56-100ng/mL

Claudin 16 (CLDN16), ELISA Kit - MBS9302114 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin 16 (CLDN16), ELISA Kit - MBS7210960 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7249210 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7202117 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7229781 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7200370 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7242627 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7237511 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7211408 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7234963 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7238063 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7213748 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Claudin-16 (CLDN16), ELISA Kit - MBS7204575 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Claudin 16 (CLDN16) - SEF296Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.53ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

Human CLDN16 ELISA Kit - E009578 from Biobool Category ELISA Kit

CNDL 16 (Claudin 16), ELISA Kit - MBS7606362 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/ml Range 0.781-50ng/ml

Rat CLDN16 / Claudin 16 ELISA Kit (Sandwich ELISA) - LS-F32229 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.469 Range 1.56-100 ng/ml

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