UBE2E3

Gene Symbol	UBE2E3
Entrez Gene	10477
Alt Symbol	UBCH9, UbcM2
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2E 3
Other Description	ubiquitin carrier protein E3|ubiquitin-conjugating enzyme E2 E3|ubiquitin-conjugating enzyme E2-23 kDa|ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)|ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5)|ubiquitin-protein ligase E3
Swissprots	Q7Z4W4 B2RAD6 Q969T4 Q5U0R7 D3DPG3
Accessions	AAY14882 EAX10989 EAX10990 Q969T4 AB017644 BAA76544 AF085362 AAD40197 AK314145 BAG36833 BC003554 AAH03554 BC003687 BC092407 AAH92407 BI257596 BM762761 BQ932163 BT019345 AAV38152 BU608985 CN369618 DA568152 DB458228 XM_005246244 XP_005246301 XM_011510492 XP_011508794 NM_001278554 NP_001265483 NM_001278555 NP_001265484 NM_006357 NP_006348 NM_182678 NP_872619
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. {ECO:0000269|PubMed:10343118, ECO:0000269|PubMed:20061386}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15545318}. Cytoplasm {ECO:0000269|PubMed:15545318}. Note=Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.
Tissue Specificity	Ubiquitously expressed at low levels. Highly expressed in skeletal muscle. {ECO:0000269|PubMed:10343118}.
Top Pathways	Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UBE2E3 293T Cell Transient Overexpression Lysate(Denatured) - H00010477-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

UBE2E3 overexpression lysate - LY405443 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

UBE2E3 293 Cell Lysate - 407797 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

UBE2E3 293 Cell Lysate - 403602 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

UBE2E3 Overexpression Lysate (Denatured) - H00010477-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

UBE2E3 Overexpression Lysate (Native) - NBL1-17525 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

UBE2E3 Overexpression Lysate (Native) - NBL1-17526 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

UBE2E3 (h): 293T Lysate - sc-111622 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

UBE2E3 Over-expression Lysate Product - GWB-D59F51 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

UBE2E3 Over-expression Lysate Product - GWB-ACDD4F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human UBE2E3 Knockdown Stable Cell Line - CSC-DC016956 from Creative biogene Category Cell Line Species Human

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