UBE2E3

Gene Symbol	UBE2E3
Entrez Gene	10477
Alt Symbol	UBCH9, UbcM2
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2E 3
Other Description	ubiquitin carrier protein E3|ubiquitin-conjugating enzyme E2 E3|ubiquitin-conjugating enzyme E2-23 kDa|ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)|ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5)|ubiquitin-protein ligase E3
Swissprots	Q7Z4W4 B2RAD6 Q969T4 Q5U0R7 D3DPG3
Accessions	AAY14882 EAX10989 EAX10990 Q969T4 AB017644 BAA76544 AF085362 AAD40197 AK314145 BAG36833 BC003554 AAH03554 BC003687 BC092407 AAH92407 BI257596 BM762761 BQ932163 BT019345 AAV38152 BU608985 CN369618 DA568152 DB458228 XM_005246244 XP_005246301 XM_011510492 XP_011508794 NM_001278554 NP_001265483 NM_001278555 NP_001265484 NM_006357 NP_006348 NM_182678 NP_872619
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. {ECO:0000269|PubMed:10343118, ECO:0000269|PubMed:20061386}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15545318}. Cytoplasm {ECO:0000269|PubMed:15545318}. Note=Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.
Tissue Specificity	Ubiquitously expressed at low levels. Highly expressed in skeletal muscle. {ECO:0000269|PubMed:10343118}.
Top Pathways	Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human UBE2E3 full length protein - ab188735 from Abcam Category Protein Prices $276.00 Sizes 50 µg Source E. coli Species Human

Human UBE2E3 full length protein - ab167930 from Abcam Category Protein Source E. coli Species Human

Human UBE2E3 full length protein - ab88285 from Abcam Category Protein Source Saccharomyces cerevisiae Species Human

Human UBE2E3 peptide - ab23036 from Abcam Category Peptide Species Human

UBE2E3 protein (His tag) - ab127408 from Abcam Category Protein Source E. coli Species Human

UBE2E3 Antibody Blocking Peptide - LS-E15852 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UBE2E3 Antibody Blocking Peptide - LS-E6912 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UBE2E3 Antibody Blocking Peptide - LS-E6913 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UBE2E3 Partial Recombinant Protein - H00010477-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

UBE2E3 Recombinant Protein - H00010477-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

UBE2E3 Peptide - P0987 from Novus Biologicals Category Peptide Species Human

UBE2E3 Peptide - P0986 from Novus Biologicals Category Peptide Species Human

UBCH9-Antibody-C-term-Blocking-Peptide - BP2170b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UBCH9-Antibody-N-term-Blocking-Peptide - BP2170a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human His6-UBE2E3, CF - E2-678-050 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal 6-His tag

Recombinant Human His6-UBE2E3, CF - E2-678-100 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal 6-His tag

Recombinant Human His6-UBE2T, CF - E2-695-050 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal 6-His tag

Recombinant Human His6-UBE2T, CF - E2-695-100 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal 6-His tag

UBE2E3 Blocking Peptide - 33R-6497 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UBE2E3 protein - 80R-4270 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

Human UBE2E3 Protein - abx060018 from Abbexa Category Protein Source Yeast Species Human

UBE2E3 Blocking Peptide - abx161233 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Zebrafish

UBE2E3 (1-207, His-tag) - AR51952PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

UBE2E3 (1-207, His-tag) - AR51952PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

UBE2E3 - H00010477-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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