UBE2E3

Gene Symbol UBE2E3
Entrez Gene 10477
Alt Symbol UBCH9, UbcM2
Species Human
Gene Type protein-coding
Description ubiquitin-conjugating enzyme E2E 3
Other Description ubiquitin carrier protein E3|ubiquitin-conjugating enzyme E2 E3|ubiquitin-conjugating enzyme E2-23 kDa|ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)|ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5)|ubiquitin-protein ligase E3
Swissprots Q7Z4W4 B2RAD6 Q969T4 Q5U0R7 D3DPG3
Accessions AAY14882 EAX10989 EAX10990 Q969T4 AB017644 BAA76544 AF085362 AAD40197 AK314145 BAG36833 BC003554 AAH03554 BC003687 BC092407 AAH92407 BI257596 BM762761 BQ932163 BT019345 AAV38152 BU608985 CN369618 DA568152 DB458228 XM_005246244 XP_005246301 XM_011510492 XP_011508794 NM_001278554 NP_001265483 NM_001278555 NP_001265484 NM_006357 NP_006348 NM_182678 NP_872619
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. {ECO:0000269|PubMed:10343118, ECO:0000269|PubMed:20061386}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15545318}. Cytoplasm {ECO:0000269|PubMed:15545318}. Note=Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.
Tissue Specificity Ubiquitously expressed at low levels. Highly expressed in skeletal muscle. {ECO:0000269|PubMed:10343118}.
Top Pathways Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

UBE2E3 CRISPR/Cas9 KO Plasmid (h) - sc-417695 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBE2E3 HDR Plasmid (h) - sc-417695-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBE2E3 Double Nickase Plasmid (h) - sc-417695-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBE2E3 Double Nickase Plasmid (h2) - sc-417695-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBE2E3 CRISPR Activation Plasmid (h) - sc-417695-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBE2E3 CRISPR Activation Plasmid (h2) - sc-417695-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBE2E3 Lentiviral Activation Particles (h) - sc-417695-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBE2E3 Lentiviral Activation Particles (h2) - sc-417695-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBE2E3 siRNA (h) - sc-61748 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UBE2E3 shRNA Plasmid (h) - sc-61748-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UBE2E3 shRNA (h) Lentiviral Particles - sc-61748-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UBE2E3 RNAi - H00010477-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

UBE2E3 RNAi - H00010477-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

UBE2E3 RNAi - H00010477-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU105701 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU105631 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22363 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04136 from Sigma-Aldrich

Category miRNA

UBE2E3 siRNA (Human) - CRH7114 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UBE2E3 - MBS8240211 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UBE2E3(NM_006357.2) - SHL110946 from Creative biogene

Category siRNA
Species Reactivities Human

Human UBE2E3 siRNA - orb267616 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UBE2E3 shRNA Plasmid (Human) - CHH7114 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UBE2E3 miRNA 3'UTR clone - MiUTR1H-10947 from Creative biogene

Species Reactivities Human
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