TYROBP

Gene Symbol TYROBP
Entrez Gene 7305
Alt Symbol DAP12, KARAP, PLOSL
Species Human
Gene Type protein-coding
Description TYRO protein tyrosine kinase binding protein
Other Description DNAX-activation protein 12|KAR-associated protein|TYRO protein tyrosine kinase-binding protein|killer-activating receptor-associated protein
Swissprots A8K2X0 O43914 Q6FGA5 Q9UMT3 F5H389
Accessions AAD09437 O43914 AF019562 AAD09436 AJ010098 CAB52288 AK290385 BAF83074 AY074782 AAL74017 BC011175 AAH11175 BI908458 BP295666 BP302545 BP305672 BQ576278 BT009851 AAP88853 CR450342 CAG29338 CR542202 CAG46999 DQ891092 ABM82018 DQ894274 ABM85200 NM_001173514 NP_001166985 NM_001173515 NP_001166986 NM_003332 NP_003323 NM_198125 NP_937758 NR_033390
Function Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Expressed in hematological cells and tissues such as peripheral blood leukocytes and spleen. Also found in bone marrow, lymph nodes, placenta, lung and liver. Expressed at lower levels in different parts of the brain especially in the basal ganglia and corpus callosum. {ECO:0000269|PubMed:11922939}.
Top Pathways Natural killer cell mediated cytotoxicity, Osteoclast differentiation

Human-TYROBP-cDNA-Clone - DC03075 from Abgent, a WuXi AppTec company

Prices $152.55
Sizes 10 µg
Species Human
Accession BC011175

TYROBP cDNA (ANA10362) - ANA10362 from Aviva Systems Biology

Prices $189.00
Sizes 1 µg
Accession BC011175

TYROBP cDNA (ANA10501) - ANA10501 from Aviva Systems Biology

Prices $189.00
Sizes 1 µg
Accession BC011175

TYROBP - MBS1269442 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC011175

Human TYROBP cDNA clone(NM_001173514.1) - CDFH020685 from Creative Biomart

Species Human
Accession NM_001173514.1

Human TYROBP cDNA clone(NM_001173515.1) - CDFH020686 from Creative Biomart

Species Human
Accession NM_001173515.1

human TYROBP ORF clone - CDCH097090 from Creative Biomart

Species Human
Accession NM_198125

human TYROBP ORF clone - CDCH097091 from Creative Biomart

Species Human
Accession NM_198125

human TYROBP ORF clone - CDCH097092 from Creative Biomart

Species Human
Accession NM_198125

human TYROBP ORF clone - CDCH097093 from Creative Biomart

Species Human
Accession NM_198125

human TYROBP ORF clone - CDCH097094 from Creative Biomart

Species Human
Accession NM_198125

human TYROBP ORF clone - CDCH097095 from Creative Biomart

Species Human
Accession NM_198125

human TYROBP ORF clone - CDCH097096 from Creative Biomart

Species Human
Accession NM_198125

human TYROBP ORF clone - CDCH097097 from Creative Biomart

Species Human
Accession NM_198125

Human TYROBP ORF Clone(NM_003332.3) - CDCL180196 from Creative Biomart

Species Human
Accession NM_003332.3

Human TYROBP ORF Clone(NM_001173514.1) - CDCR356789 from Creative Biomart

Species Human
Accession NM_001173514.1

Human TYROBP ORF Clone(NM_001173514.1) - CDCR356790 from Creative Biomart

Species Human
Accession NM_001173514.1

Human TYROBP ORF Clone(NM_001173515.1) - CDCR356832 from Creative Biomart

Species Human
Accession NM_001173515.1

Human TYROBP ORF Clone(NM_001173515.1) - CDCR356833 from Creative Biomart

Species Human
Accession NM_001173515.1

human TYROBP ORF clone (NM_001173514.1) - CDCH097094 from Creative biogene

Species Human

human TYROBP ORF clone (NM_001173515.1) - CDCH097096 from Creative biogene

Species Human

Human TYROBP ORF Clone (BC011175) - CDCS417769 from Creative biogene

Species Human
Accession O43914

Human TYROBP cDNA Clone(NM_001173514.1) - CDFH020685 from Creative biogene

Species Human

Human TYROBP cDNA Clone(NM_001173515.1) - CDFH020686 from Creative biogene

Species Human
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