GRM5

Gene Symbol	GRM5
Entrez Gene	2915
Alt Symbol	GPRC1E, MGLUR5, PPP1R86, mGlu5
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, metabotropic 5
Other Description	metabotropic glutamate receptor 5|protein phosphatase 1, regulatory subunit 86
Swissprots	Q6J164 P41594
Accessions	EAW59358 EAW59359 P41594 AF052171 AK291362 BAF84051 AW297388 AY608336 AAT37960 BC031602 BC047497 BX282658 CR627311 D28538 BAA05891 D28539 BAA05892 DA316590 DR002861 FJ588505 ACU31022 FJ588506 ACU31023 FJ588507 ACU31024 FJ668670 ACV89822 S64316 AAD13954 U79242 XM_006718828 XP_006718891 XM_011542792 XP_011541094 XM_011542793 XP_011541095 XM_011542794 XP_011541096 XM_011542795 XP_011541097 NM_000842 NP_000833 NM_001143831 NP_001137303
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}; Multi-pass membrane protein {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}.
Top Pathways	Gap junction, Long-term potentiation, Huntington's disease, Calcium signaling pathway, Glutamatergic synapse

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Metabotropic Glutamate Receptor 5 protein fragment - ab158589 from Abcam Category Protein Source Wheat germ Species Human

Metabotropic Glutamate Receptor 5 peptide - ab139974 from Abcam Category Peptide

Rat Metabotropic Glutamate Receptor 5 (phospho S996) peptide - ab17573 from Abcam Category Peptide Source CHO

Rat Metabotropic Glutamate Receptor 5 peptide - ab17575 from Abcam Category Peptide

GRM5 / MGLUR5 Antibody Blocking Peptide - LS-E8212 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRM5 / MGLUR5 Antibody Blocking Peptide - LS-E29491 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM5 / MGLUR5 Antibody Blocking Peptide - LS-E29503 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM5 / MGLUR5 Antibody Blocking Peptide - LS-E29507 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human mGluR5 Protein - H00002915-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Metabotropic-Glutamate-Receptor-5-GPRC1E-Antibody-C-term-T1003-Blocking-peptide - BP6345a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

mGLUR5 Blocking Peptide - abx062700 from Abbexa Category Peptide Species Human, Mouse, Rat, Dog, Monkey, Pig

mGLUR5 Blocking Peptide - abx062126 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken

mGluR5 / GRM5 - H00002915-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

mGluR5 / GRM5 - H00002915-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

mGLUR5 Blocking Peptide - CBP1506 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Dog, Monkey, Pig

mGLUR5 Blocking Peptide - CBP3232 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Chicken

mGluR-5 (K56) Peptide - BS2732P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Metabotropic-Glutamate-Receptor-5-GPRC1E-Antibody-C-term-E1127-Blocking-peptide - BP6345b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GRM5 Peptide, Human - M34GP06677H from Creative Peptides Category Peptide Source Synthetic. Species Human

GRM5 peptide - orb217369 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey, Drosophila

Recombinant Human mGluR5 Protein, CF - 9529-UR from R&D Systems Category Protein Prices $599.00 Sizes 100 µg Source Mouse myeloma cell line, NS0-derived Ser19-Ser509, with a C-terminal 6-His tag Species Human

Metabotropic glutamate receptor 5 (GRM5), partial, Recombinant Protein - MBS960840 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human mGluR5 Protein, CF - 9529-UR from Novus Biologicals Category Protein Prices $599.00 Sizes 100 µg Species Human

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