GRM5

Gene Symbol GRM5
Entrez Gene 2915
Alt Symbol GPRC1E, MGLUR5, PPP1R86, mGlu5
Species Human
Gene Type protein-coding
Description glutamate receptor, metabotropic 5
Other Description metabotropic glutamate receptor 5|protein phosphatase 1, regulatory subunit 86
Swissprots Q6J164 P41594
Accessions EAW59358 EAW59359 P41594 AF052171 AK291362 BAF84051 AW297388 AY608336 AAT37960 BC031602 BC047497 BX282658 CR627311 D28538 BAA05891 D28539 BAA05892 DA316590 DR002861 FJ588505 ACU31022 FJ588506 ACU31023 FJ588507 ACU31024 FJ668670 ACV89822 S64316 AAD13954 U79242 XM_006718828 XP_006718891 XM_011542792 XP_011541094 XM_011542793 XP_011541095 XM_011542794 XP_011541096 XM_011542795 XP_011541097 NM_000842 NP_000833 NM_001143831 NP_001137303
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}; Multi-pass membrane protein {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}.
Top Pathways Gap junction, Long-term potentiation, Huntington's disease, Calcium signaling pathway, Glutamatergic synapse

mGluR-5 CRISPR/Cas9 KO Plasmid (h) - sc-401460 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-5 HDR Plasmid (h) - sc-401460-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-5 Double Nickase Plasmid (h) - sc-401460-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-5 Double Nickase Plasmid (h2) - sc-401460-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-5 CRISPR Activation Plasmid (h) - sc-401460-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-5 CRISPR Activation Plasmid (h2) - sc-401460-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-5 Lentiviral Activation Particles (h) - sc-401460-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-5 Lentiviral Activation Particles (h2) - sc-401460-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-5 siRNA (h) - sc-61034 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR-5 shRNA Plasmid (h) - sc-61034-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR-5 shRNA (h) Lentiviral Particles - sc-61034-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR5 RNAi - H00002915-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU082581 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9705 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9705 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06837 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06837

GRM5 siRNA (Human) - CRH1968 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GRM5 - MBS8217171 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human GRM5 siRNA - orb262470 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GRM5 shRNA Plasmid (Human) - CHH1968 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GRM5 miRNA 3'UTR clone - MiUTR4H-TG04003 from Creative biogene

Species Reactivities Human
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