TRADD

Gene Symbol	TRADD
Entrez Gene	8717
Alt Symbol	Hs.89862
Species	Human
Gene Type	protein-coding
Description	TNFRSF1A-associated via death domain
Other Description	TNFR1-associated death domain protein\|tumor necrosis factor receptor type 1 associated death domain protein\|tumor necrosis factor receptor type 1-associated DEATH domain protein\|tumor necrosis factor receptor-1-associated protein
Swissprots	Q15628 B3KQZ9 Q52NZ1 B2RDS3
Accessions	AAS68637 AAX89407 CAC38018 CBW52910 EAW83081 Q15628 AK090673 BAG52211 AK301593 BAG63082 AK315654 BAG38020 BC004491 AAH04491 BG717460 BQ707739 BT006934 AAP35580 CA426418 DA353575 DQ893419 ABM84345 DQ896738 ABM87737 L41690 AAA98482 XM_005256213 XP_005256270 XM_011523420 XP_011521722 NM_003789 NP_003780 NM_153425
Function	The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000269\|PubMed:11684708}. Note=Shuttles between the cytoplasm and the nucleus. {ECO:0000250}.
Tissue Specificity	Found in all examined tissues.
Top Pathways	Sphingolipid signaling pathway, Apoptosis, TNF signaling pathway, Epstein-Barr virus infection, Viral carcinogenesis

TRADD - MBS1275802 from MyBioSource

Species	Human
Accession	BC004491

human TRADD ORF clone - CDCH093524 from Creative Biomart

human TRADD ORF clone - CDCH093525 from Creative Biomart

Species	Human
Accession	NM_003789

Human TRADD ORF Clone(NM_003789.3) - CDCL179482 from Creative Biomart

Species	Human
Accession	NM_003789.3

Human TRADD ORF Clone(NM_003789.3) - CDCR286479 from Creative Biomart

Species	Human
Accession	NM_003789.3

Human TRADD ORF Clone(NM_003789.3) - CDCR286480 from Creative Biomart

Species	Human
Accession	NM_003789.3

Human TRADD Gene ORF cDNA clone in cloning vector - HG13888-G from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13888-NF from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, N-HA tag - HG13888-NY from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13888-NM from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13888-CF from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13888-ACG from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13888-CM from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13888-ANG from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13888-ACR from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13888-ANR from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, C-HA tag - HG13888-CY from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, N-His tag - HG13888-NH from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid - HG13888-UT from Sino Biological

Species	Human

Human TRADD Gene ORF cDNA clone expression plasmid, C-His tag - HG13888-CH from Sino Biological

Species	Human

Human TRADD ORF Clone(NM_003789.3) - CDCR286479 from Creative biogene

Species	Human

Human TRADD ORF Clone (BC004491) - CDCS411460 from Creative biogene

Species	Human
Accession	Q15628

Human TRADD ORF clone (BC004491) - CDCB159572 from Creative biogene

Species	Human

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