IL23A

Gene Symbol	IL23A
Entrez Gene	51561
Alt Symbol	IL-23, IL-23A, IL23P19, P19, SGRF
Species	Human
Gene Type	protein-coding
Description	interleukin 23, alpha subunit p19
Other Description	IL-23 subunit alpha|IL-23-A|IL-23p19|JKA3 induced upon T-cell activation|interleukin 23 p19 subunit|interleukin-23 subunit alpha|interleukin-23 subunit p19|interleukin-six, G-CSF related factor
Swissprots	Q9H2A5 Q6NZ82 Q6NZ80 Q9NPF7
Accessions	BAA93687 CAM82731 CBX47553 CCA63964 EAW96933 Q9NPF7 AB030000 BAA93686 AF301620 AAG37232 AJ506993 CAD45088 AY359083 AAQ89442 BC066267 AAH66267 BC066268 AAH66268 BC066269 AAH66269 BC067511 AAH67511 BC067512 AAH67512 BC067513 AAH67513 BM842783 BM851337 HQ447589 ADQ32075 U38443 XM_011538477 XP_011536779 NM_016584 NP_057668
Function	Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. {ECO:0000269|PubMed:11114383, ECO:0000269|PubMed:12023369, ECO:0000269|PubMed:16424222}.
Subcellular Location	Secreted {ECO:0000269|PubMed:11114383}. Note=Secreted upon association with IL12B.
Tissue Specificity	Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level). {ECO:0000269|PubMed:11114383, ECO:0000269|PubMed:16424222}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Rheumatoid arthritis, Pertussis, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL-23 (Interleukin-23) Human ELISA Kit - ab64708 from Abcam Category ELISA Kit Prices $489.00, $734.00 Sizes 1 x 96 tests, 2 x 96 tests Sensitivity < 20 pg/ml Range 156.2 pg/ml - 5000 pg/ml

Mouse IL23A / IL-23 p19 ELISA Kit (Sandwich ELISA) - LS-F2730 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 2 pg/ml Range 63-8000 pg/ml

Rat IL23A / IL-23 p19 ELISA Kit (Sandwich ELISA) - LS-F4187 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 63-8000 pg/ml

Human IL23A / IL-23 p19 ELISA Kit (Sandwich ELISA) - LS-F4186 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 12.2 pg/ml Range 63-8000 pg/ml

Mouse IL23A / IL-23 p19 ELISA Kit (Sandwich ELISA) - LS-F4188 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 7.8 pg/ml Range 63-8000 pg/ml

Human IL23A / IL-23 p19 ELISA Kit (Sandwich ELISA) - LS-F643 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 63-8000 pg/ml

Mouse IL23A / IL-23 p19 ELISA Kit (Sandwich ELISA) - LS-F668 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 63-8000 pg/ml

Human IL23A / IL-23 p19 ELISA Kit (Sandwich ELISA) - LS-F11768 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 Range 63-8000 pg/ml

Human IL23A / Interleukin-23 Subunit Alpha ELISA Kit - RAB0697 from Sigma-Aldrich Category ELISA Kit Prices $479.00 Sizes 1 kt

Human IL-23 HS Magnetic Luminex Performance Assay - LBHS1716 from R&D Systems

Human IL-23 Quantikine ELISA Kit - D2300B from R&D Systems Category ELISA Kit Prices $509.00, $2,440.00, $16,540.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 16.3 pg/mL Range 39.0 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Human IL-23 Quantikine PharmPak (50 Plates) - PD2300B from R&D Systems Category ELISA Kit Sensitivity 16.3 pg/mL Range 39 - 2,500 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma)

Human IL-23 Quantikine SixPak (6 Plates) - S2300B from R&D Systems Category ELISA Kit Sensitivity 16.3 pg/mL Range 39 - 2,500 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma)

Mouse IL-23 Quantikine ELISA Kit - M2300 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 4.17 pg/mL Range 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, Heparin Plasma)

Mouse IL-23 DuoSet ELISA - DY1887 from R&D Systems Category ELISA Kit Prices $249.00, $649.00 Sizes 1 kit (for 5 Plates), 1 kit (for 15 Plates) Range 39.10 - 2,500 pg/mL

Human IL-23 DuoSet ELISA - DY1290 from R&D Systems Category ELISA Kit Prices $249.00, $649.00 Sizes 1 kit (for 5 Plates), 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Mouse IL-23 DuoSet, 5 Plate - DY1887-05 from R&D Systems Category ELISA Kit

Human IL-23 DuoSet, 5 Plate - DY1290-05 from R&D Systems Category ELISA Kit

IL-23 ELISA Kit (Human) : 96 Wells (OKAG00143) - OKAG00143 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 63 pg/mL Range 63-8,000 pg/mL

Human IL-23 ELISA kit - orb158963 from Biorbyt Category ELISA Kit Prices $859.00, $1,471.00, $3,154.00 Sizes 96 well, 192 assays, 480 assays

Human IL-23 ELISA Kit - abx056226 from Abbexa Category ELISA Kit

Interleukin 23, IL-23, Human, ELISA Kit - E-EL-H0107 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 23.438 Range 39.063-2500pg/mL

IL-23, Human, ELISA - IB49678 from ARP American Research Products Category ELISA Kit Prices $802.00 Sizes 96 t

Interleukin 23 (IL23), Human, ELISA Kit - SEA384Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 6.2pg/mL Range 15.6-1,000pg/mL

Interleukin-23 subunit alpha (IL-23A), Human, ELISA Kit - CSB-E17339h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

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