NMRK2

Gene Symbol NMRK2
Entrez Gene 27231
Alt Symbol ITGB1BP3, MIBP, NRK2
Species Human
Gene Type protein-coding
Description nicotinamide riboside kinase 2
Other Description NRK 2|RNK 2|integrin beta-1-binding protein 3|muscle-specific beta 1 integrin binding protein|nicotinic acid riboside kinase 2|nmR-K 2|ribosylnicotinamide kinase 2|ribosylnicotinic acid kinase 2
Swissprots Q9NZK3 Q52M81 B7ZKR3 Q9NPI5
Accessions CAM12701 EAW69277 EAW69278 EAW69279 Q9NPI5 AF190819 AAF26711 AK001663 BAA91820 AK022514 BAB14071 AL365377 CAB96949 AY611481 AAT11929 BC093637 AAH93637 BC101575 AAI01576 BC143329 AAI43330 BM669267 BM717225 XM_006722725 XP_006722788 XM_006722726 XP_006722789 NM_014446 NM_001289117 NP_001276046 NM_170678 NP_733778 NR_110316
Function Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis. {ECO:0000269|PubMed:10613898, ECO:0000269|PubMed:15137942}.
Tissue Specificity Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta. {ECO:0000269|PubMed:10613898}.
Top Pathways Nicotinate and nicotinamide metabolism

MIBP (C-14) - sc-240682 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MIBP (G-13) - sc-240681 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MIBP (G-13): sc-240681. Western blot analysis of MIBP expression in mouse brain tissue extract.

Anti-ITGB1BP3 antibody - ab69417 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ITGB1BP3 antibody (ab69417) at 1/500 dilutionLane 1 : ITGB1BP3 transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-ITGB1BP3 antibody - ab99228 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ITGB1BP3 antibody (ab99228) at 1 µg/ml + Human fetal thymus lysate at 10 µg

Anti-ITGB1BP3 antibody - N-terminal - ab77573 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab77573 at 1/10 dilution, staining ITGB1BP3 in human skeletal muscle by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-MIBP / ITGB1BP3 Antibody - LS-C310791 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MIBP / ITGB1BP3 Antibody - LS-C308544 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MIBP / ITGB1BP3 Antibody (clone 5B4.7) - LS-C179614 from LifeSpan Bioscience

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B4.7

Anti-MIBP / ITGB1BP3 Antibody (aa107-156) - LS-C110714 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ITGB1BP3 antibody LS-C110714 Western blot of Fetal Thymus lysate.

Anti-MIBP / ITGB1BP3 Antibody (aa27-55) - LS-C97276 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with ITGB1BP3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-MIBP / ITGB1BP3 Antibody (aa164-194) - LS-C165323 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ITGB1BP3 Antibody western blot of mouse testis tissue lysates (35 ug/lane). This demonstrates ITGB1BP3 antibody detected ITGB1BP3 protein (arrow).

ITGB1BP3 Antibody - NBP1-53033 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

ITGB1BP3 Antibody - NBP2-14135 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: ITGB1BP3 Antibody [NBP2-14135] - Staining of human testis shows strong cytoplasmic positivity in Leydig cells.

ITGB1BP3 Antibody - H00027231-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

ITGB1BP3 Antibody - H00027231-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ITGB1BP3 Antibody [H00027231-D01P] - Analysis of ITGB1BP3 expression in transfected 293T cell line by ITGB1BP3 polyclonal antibody.Lane 1: ITGB1BP3 transfected lysate(26.00 KDa).Lane 2: Non-transfected lysate.

Anti-ITGB1BP3 antibody produced in rabbit - SAB1410538 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ITGB1BP3: <B>Cat. No. SAB1410538</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~26 kDa using ITGB1BP3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-ITGB1BP3 (N-term) antibody produced in rabbit - SAB1300697 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ITGB1BP3 (N-term) Antibody: <B>Cat. No. SAB1300697</B>: ITGB1BP3 in human skeletal muscle tissue with Anti-ITGB1BP3 (N-term) Antibody at 40 μg/mL.

Anti-ITGB1BP3 antibody produced in mouse - SAB1407344 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ITGB1BP3: <B>Cat. No. SAB1407344</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~25.3 kDa using ITGB1BP3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

ITGB1BP3 antibody - middle region (ARP42714_P050) - ARP42714_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ITGB1BP3 Antibody - N-terminal region (OAAB01493) - OAAB01493 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ITGB1BP3 Antibody - middle region (OAAB01494) - OAAB01494 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ITGB1BP3-Antibody-Center - AP2791c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ITGB1BP3 Antibody (Center) (Cat. #AP2791c) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates ITGB1BP3 antibody detected ITGB1BP3 protein (arrow).

ITGB1BP3-Antibody-N-term - AP2791a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ITGB1BP3 Antibody (N-term) (Cat. #AP2791a) in K562 cell line lysates (35ug/lane). ITGB1BP3 (arrow) was detected using the purified Pab.

ITGB1BP3 antibody, Internal - GTX46967 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
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