KYNU

Gene Symbol	KYNU
Entrez Gene	8942
Alt Symbol	KYNUU
Species	Human
Gene Type	protein-coding
Description	kynureninase
Other Description	L-kynurenine hydrolase
Swissprots	B2RCZ5 Q9BVW3 D3DP79 Q6I9T2 Q16719
Accessions	AAX93159 AAY14727 EAX11599 EAX11600 EAX11601 Q16719 AK223426 BAD97146 AK290900 BAF83589 AK292095 BAF84784 AK315343 BAG37742 AL548658 AW290980 AW296221 BC000879 AAH00879 CB151988 CR457423 CAG33704 HQ447861 ADQ32345 U57721 AAC50650 XM_011512101 XP_011510403 XM_011512102 XP_011510404 XM_011512103 XP_011510405 XM_011512104 XP_011510406 XM_011512105 XP_011510407 XR_923058 NM_001032998 NP_001028170 NM_001199241 NP_001186170 NM_003937 NP_003928
Function	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Subcellular Location	Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03017, ECO:0000269|PubMed:8706755}.
Tissue Specificity	Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions. {ECO:0000269|PubMed:8706755, ECO:0000269|PubMed:9180257}.
Top Pathways	Tryptophan metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Kynureninase gene - orb91498 from Biorbyt Prices $366.00 Sizes 10 μg Species Human

Human-KYNU-cDNA-Clone - DC00413 from Abgent, a WuXi AppTec company Prices $414.45 Sizes 10 µg Species Human Accession BC000879

KYNU - MBS1273051 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC000879

Human KYNU cDNA clone(NM_001032998.1) - CDFH010145 from Creative Biomart Species Human Accession NM_001032998.1

Human KYNU cDNA clone(NM_003937.2) - CDFH010146 from Creative Biomart Species Human Accession NM_003937.2

Human KYNU ORF Clone(NM_003937.2) - CDCL168393 from Creative Biomart Species Human Accession NM_003937.2

Human KYNU ORF Clone(NM_001032998.1) - CDCL168394 from Creative Biomart Species Human Accession NM_001032998.1

Human KYNU ORF Clone(NM_003937.2) - CDCR286803 from Creative Biomart Species Human Accession NM_003937.2

Human KYNU ORF Clone(NM_003937.2) - CDCR286804 from Creative Biomart Species Human Accession NM_003937.2

Human KYNU ORF Clone(NM_001032998.1) - CDCR343027 from Creative Biomart Species Human Accession NM_001032998.1

Human KYNU ORF Clone(NM_001032998.1) - CDCR343028 from Creative Biomart Species Human Accession NM_001032998.1

Human KYNU ORF Clone(NM_001032998.1) - CDCR343029 from Creative Biomart Species Human Accession NM_001032998.1

Human KYNU Gene ORF cDNA clone in cloning vector - HG10841-M from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, C-His tag - HG10841-CH from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10841-M-F from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10841-ANG from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10841-ACR from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10841-ANR from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10841-ACG from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid - HG10841-UT from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10841-NF from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10841-NM from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, C-HA tag - HG10841-CY from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10841-CF from Sino Biological Species Human

Human KYNU Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10841-CM from Sino Biological Species Human

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