KYNU

Gene Symbol	KYNU
Entrez Gene	8942
Alt Symbol	KYNUU
Species	Human
Gene Type	protein-coding
Description	kynureninase
Other Description	L-kynurenine hydrolase
Swissprots	B2RCZ5 Q9BVW3 D3DP79 Q6I9T2 Q16719
Accessions	AAX93159 AAY14727 EAX11599 EAX11600 EAX11601 Q16719 AK223426 BAD97146 AK290900 BAF83589 AK292095 BAF84784 AK315343 BAG37742 AL548658 AW290980 AW296221 BC000879 AAH00879 CB151988 CR457423 CAG33704 HQ447861 ADQ32345 U57721 AAC50650 XM_011512101 XP_011510403 XM_011512102 XP_011510404 XM_011512103 XP_011510405 XM_011512104 XP_011510406 XM_011512105 XP_011510407 XR_923058 NM_001032998 NP_001028170 NM_001199241 NP_001186170 NM_003937 NP_003928
Function	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Subcellular Location	Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03017, ECO:0000269|PubMed:8706755}.
Tissue Specificity	Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions. {ECO:0000269|PubMed:8706755, ECO:0000269|PubMed:9180257}.
Top Pathways	Tryptophan metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human L-Kynurenine Hydrolase full length protein - ab160275 from Abcam Category Protein Source Wheat germ Species Human

Human L-Kynurenine Hydrolase protein fragment - ab160276 from Abcam Category Protein Source Wheat germ Species Human

KYNU Antibody Blocking Peptide - LS-E8446 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KYNU Antibody Blocking Peptide - LS-E16770 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KYNU Antibody Blocking Peptide - LS-E16771 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Kynureninase Recombinant Protein - H00008942-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Kynureninase Partial Recombinant Protein - H00008942-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

KYNU-Antibody-C-term-Blocking-Peptide - BP6768b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Kynureninase, CF - 4887-KH-010 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Met1-Asn465, with a C-terminal 10-His tag

Human Kynureninase protein (His Tag) - orb139261 from Biorbyt Category Protein Prices $400.00, $527.00 Sizes 10 μg, 20 μg Source Baculovirus-Insect Cells Species Human

KYNU Blocking Peptide - 33R-5947 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KYNU Blocking Peptide - 33R-4774 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Kynureninase - H00008942-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Kynureninase - H00008942-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Kynureninase - H00008942-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Kynureninase - H00008942-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

KYNU fusion protein - ag2365 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Kynureninase, Carrier Free - KYNU-11H from Creative Biomart Category Protein Source Sf 21 Species Human

Recombinant Human KYNU, His-tagged - KYNU-541H from Creative Biomart Category Protein Source Baculovirus Sf21 Insect Cells Species Human

Recombinant Human Kynureninase, His-tagged - KYNU-1349H from Creative Biomart Category Protein Source Baculovirus-Insect cells Species Human

Recombinant Kynureninase (KYNU) - RPD762Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Human KYNU / Kynureninase Protein (His Tag) - 10841-H08B-10 from Sino Biological Category Protein Prices $178.00, $248.00 Sizes 10 µg, 20 µg Source Baculovirus-Insect Cells Species Human

Recombinant Kynureninase (KYNU) - RPD762Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Kynureninase(kynU) - CSB-YP770648BQE CSB-EP770648BQE CSB-BP770648BQE CSB-MP770648BQE from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Bacillus

Recombinant Kynureninase(kynU) - CSB-YP685987XBB CSB-EP685987XBB CSB-BP685987XBB CSB-MP685987XBB from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Xanthomonas

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