CWC22

Gene Symbol CWC22
Entrez Gene 57703
Alt Symbol EIF4GL, NCM, fSAPb
Species Human
Gene Type protein-coding
Description CWC22 spliceosome-associated protein
Other Description CWC22 spliceosome-associated protein homolog|functional spliceosome-associated protein b|nucampholin homolog|pre-mRNA-splicing factor CWC22 homolog
Swissprots Q05DC2 Q4G135 Q7Z6I0 Q9H6Q6 Q9HCG8 Q6PEX2 Q9H5L3 Q52LF0
Accessions EAX10996 EAX10997 EAX10998 Q9HCG8 AB046824 BAB13430 AK025635 BAB15197 AK026978 BAB15612 AK123647 BC016651 AAH16651 BC031216 AAH31216 BC041662 BC053573 AAH53573 BC057826 AAH57826 BC093952 AAH93952 BC093954 AAH93954 BC143433 BF699499 XM_005246726 XP_005246783 NM_020943 NP_065994
Function Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. {ECO:0000269|PubMed:22959432, ECO:0000269|PubMed:22961380, ECO:0000269|PubMed:23236153}.
Subcellular Location Nucleus. Nucleus speckle. Note=Concentrates around speckles, which are sites of pre-mRNA synthesis and processing, where it colocalizes with EJC core proteins.

KIAA1604 293T Cell Transient Overexpression Lysate(Denatured) - H00057703-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

CWC22 overexpression lysate - LY412191 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CWC22 293 Cell Lysate - 406041 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CWC22 Overexpression Lysate (Native) - NBL1-12271 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

CWC22 Over-expression Lysate Product - GWB-BEC302 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

CWC22 Overexpression Lysate (Denatured) - H00057703-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

CWC22 Overexpression Lysate (Denatured) - H00057703-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human CWC22 Knockdown Stable Cell Line - CSC-DC003852 from Creative biogene

Category Cell Line
Species Human
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