CWC22

Gene Symbol CWC22
Entrez Gene 57703
Alt Symbol EIF4GL, NCM, fSAPb
Species Human
Gene Type protein-coding
Description CWC22 spliceosome-associated protein
Other Description CWC22 spliceosome-associated protein homolog|functional spliceosome-associated protein b|nucampholin homolog|pre-mRNA-splicing factor CWC22 homolog
Swissprots Q05DC2 Q4G135 Q7Z6I0 Q9H6Q6 Q9HCG8 Q6PEX2 Q9H5L3 Q52LF0
Accessions EAX10996 EAX10997 EAX10998 Q9HCG8 AB046824 BAB13430 AK025635 BAB15197 AK026978 BAB15612 AK123647 BC016651 AAH16651 BC031216 AAH31216 BC041662 BC053573 AAH53573 BC057826 AAH57826 BC093952 AAH93952 BC093954 AAH93954 BC143433 BF699499 XM_005246726 XP_005246783 NM_020943 NP_065994
Function Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. {ECO:0000269|PubMed:22959432, ECO:0000269|PubMed:22961380, ECO:0000269|PubMed:23236153}.
Subcellular Location Nucleus. Nucleus speckle. Note=Concentrates around speckles, which are sites of pre-mRNA synthesis and processing, where it colocalizes with EJC core proteins.

CWC22 (A-6) - sc-398178 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CWC22 (A-6): sc-398178. Western blot analysis of CWC22 expression in HeLa (A) and Jurkat (B) whole cell lysates.

CWC22 (K-20) - sc-242525 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CWC22 (K-20): sc-242525. Western blot analysis of CWC22 expression in IMR-32 whole cell lysate.

CWC22 (H-300) - sc-382008 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CWC22 (N-20) - sc-242523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CWC22 (N-20): sc-242523. Western blot analysis of CWC22 expression in HeLa (A) and IMR-32 (B) nuclear extracts.

Anti-CWC22 antibody - ab88689 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-CWC22 antibody (ab88689) at 1 µg/ml + Jurkat cell lysate at 50 µg

Anti-CWC22 antibody - ab106988 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CWC22 antibody (ab106988) at 1/100 dilution + Jurkat cell line lysate at 35 µg

Anti-CWC22 Antibody (aa19-49, AP) - LS-C234361 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CWC22 Antibody (aa19-49, Biotin) - LS-C234363 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CWC22 Antibody (aa19-49, FITC) - LS-C234364 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CWC22 Antibody (aa19-49, APC) - LS-C234362 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CWC22 Antibody (aa19-49, Azide-free, HRP) - LS-C249782 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CWC22 Antibody (aa19-49) - LS-C320694 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CWC22 Antibody (aa19-49, PE) - LS-C234365 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CWC22 Antibody - LS-C308632 from LifeSpan Bioscience

Host Mouse
Clonality Polyclonal

Anti-CWC22 Antibody (C-Terminus) - LS-C135105 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CWC22 antibody LS-C135105 Western blot of HeLa lysate.

Anti-CWC22 Antibody (aa19-49) - LS-C167165 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CWC22 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

CWC22 Antibody - NBP1-84864 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CWC22 Antibody - H00057703-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: CWC22 Antibody [H00057703-B01P] - Analysis of CWC22 expression in Jurkat.

CWC22 Antibody - NBP1-69211 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CWC22 Antibody [NBP1-69211] - Hela cell lysate, concentration 0.2-1 ug/ml.

CWC22 Polyclonal Antibody - bs-11464R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CWC22 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11464R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CWC22 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11464R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CWC22 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11464R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CWC22 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11464R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CWC22 Polyclonal Antibody, Cy3 Conjugated - bs-11464R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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