CWC22

Gene Symbol CWC22
Entrez Gene 57703
Alt Symbol EIF4GL, NCM, fSAPb
Species Human
Gene Type protein-coding
Description CWC22 spliceosome-associated protein
Other Description CWC22 spliceosome-associated protein homolog|functional spliceosome-associated protein b|nucampholin homolog|pre-mRNA-splicing factor CWC22 homolog
Swissprots Q05DC2 Q4G135 Q7Z6I0 Q9H6Q6 Q9HCG8 Q6PEX2 Q9H5L3 Q52LF0
Accessions EAX10996 EAX10997 EAX10998 Q9HCG8 AB046824 BAB13430 AK025635 BAB15197 AK026978 BAB15612 AK123647 BC016651 AAH16651 BC031216 AAH31216 BC041662 BC053573 AAH53573 BC057826 AAH57826 BC093952 AAH93952 BC093954 AAH93954 BC143433 BF699499 XM_005246726 XP_005246783 NM_020943 NP_065994
Function Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. {ECO:0000269|PubMed:22959432, ECO:0000269|PubMed:22961380, ECO:0000269|PubMed:23236153}.
Subcellular Location Nucleus. Nucleus speckle. Note=Concentrates around speckles, which are sites of pre-mRNA synthesis and processing, where it colocalizes with EJC core proteins.

CWC22 CRISPR/Cas9 KO Plasmid (h) - sc-412881 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CWC22 HDR Plasmid (h) - sc-412881-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CWC22 Double Nickase Plasmid (h) - sc-412881-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CWC22 Double Nickase Plasmid (h2) - sc-412881-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CWC22 CRISPR Activation Plasmid (h) - sc-412881-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CWC22 CRISPR Activation Plasmid (h2) - sc-412881-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CWC22 Lentiviral Activation Particles (h) - sc-412881-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CWC22 Lentiviral Activation Particles (h2) - sc-412881-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CWC22 siRNA (h) - sc-94265 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CWC22 shRNA Plasmid (h) - sc-94265-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CWC22 shRNA (h) Lentiviral Particles - sc-94265-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CWC22 RNAi - H00057703-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU005901 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6786 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6786 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02596 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02596

CWC22 siRNA (Human) - CRJ1645 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CWC22 - MBS8213578 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CWC22 (NM_020943.2) - SHH272001 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human KIAA1604(NM_020943.2) - SHL196032 from Creative biogene

Category siRNA
Species Reactivities Human

Human CWC22 siRNA - orb272146 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CWC22 shRNA Plasmid (Human) - CHJ1645 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CWC22 miRNA 3'UTR clone - MiUTR1H-05273 from Creative biogene

Species Reactivities Human
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