CWC22

Gene Symbol	CWC22
Entrez Gene	57703
Alt Symbol	EIF4GL, NCM, fSAPb
Species	Human
Gene Type	protein-coding
Description	CWC22 spliceosome-associated protein
Other Description	CWC22 spliceosome-associated protein homolog|functional spliceosome-associated protein b|nucampholin homolog|pre-mRNA-splicing factor CWC22 homolog
Swissprots	Q05DC2 Q4G135 Q7Z6I0 Q9H6Q6 Q9HCG8 Q6PEX2 Q9H5L3 Q52LF0
Accessions	EAX10996 EAX10997 EAX10998 Q9HCG8 AB046824 BAB13430 AK025635 BAB15197 AK026978 BAB15612 AK123647 BC016651 AAH16651 BC031216 AAH31216 BC041662 BC053573 AAH53573 BC057826 AAH57826 BC093952 AAH93952 BC093954 AAH93954 BC143433 BF699499 XM_005246726 XP_005246783 NM_020943 NP_065994
Function	Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. {ECO:0000269|PubMed:22959432, ECO:0000269|PubMed:22961380, ECO:0000269|PubMed:23236153}.
Subcellular Location	Nucleus. Nucleus speckle. Note=Concentrates around speckles, which are sites of pre-mRNA synthesis and processing, where it colocalizes with EJC core proteins.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CWC22 full length protein - ab163630 from Abcam Category Protein Source Wheat germ Species Human

CWC22 Antibody Blocking Peptide - LS-E496 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CWC22 Antibody Blocking Peptide - LS-E15023 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CWC22 Protein - H00057703-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CWC22-Antibody-N-term-Blocking-peptide - BP10788a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KIAA1604 Blocking Peptide - 33R-8191 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CWC22 - H00057703-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CWC22 - H00057703-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Recombinant Human Pre-mRNA-splicing factor CWC22 homolog(CWC22) ,partial - CSB-YP875721HU CSB-EP875721HU CSB-BP875721HU CSB-MP875721HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Pre-mRNA-splicing factor CWC22 homolog (CWC22), partial, Recombinant Protein - MBS1354471 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CWC22 Recombinant Protein Antigen - NBP1-84864PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CWC22 fusion protein - Ag25466 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

CWC22 Peptide, Human - M34GP03852H from Creative Peptides Category Peptide Source Synthetic. Species Human

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