IL34

Gene Symbol	IL34
Entrez Gene	146433
Alt Symbol	C16orf77, IL-34
Species	Human
Gene Type	protein-coding
Description	interleukin 34
Other Description	interleukin-34
Swissprots	B2Z4A8 B2ZC70 B2RC28 Q8N6L2 Q6ZMJ4
Accessions	EAW51800 EAW51801 EAW51802 Q6ZMJ4 AK172744 BAD18731 AK307727 AK308799 AK314913 BAG37425 AW292500 BC029804 AAH29804 BQ709387 CD248375 CD515627 EU599219 ACD13474 EU636994 ACD13452 XM_011522902 XP_011521204 XM_011522903 XP_011521205 XM_011522904 XP_011521206 NM_001172771 NP_001166242 NM_001172772 NP_001166243 NM_152456 NP_689669
Function	Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. {ECO:0000269|PubMed:18467591, ECO:0000269|PubMed:20489731, ECO:0000269|PubMed:20504948, ECO:0000269|PubMed:20829061}.
Subcellular Location	Secreted {ECO:0000269|PubMed:18467591}.
Tissue Specificity	Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon. {ECO:0000269|PubMed:18467591}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL34 ELISA Kit (Sandwich ELISA) - LS-F5415 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 5.8 pg/ml Range 3.908-125 pg/ml

Mouse IL34 ELISA Kit (Sandwich ELISA) - LS-F5416 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 3.3 pg/ml Range 3.908-125 pg/ml

Human IL34 ELISA Kit (Sandwich ELISA) - LS-F647 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 3.908-125 pg/ml

Human IL34 ELISA Kit (Sandwich ELISA) - LS-F355 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 3.908 pg/ml Range 3.908-125 pg/ml

Rat IL34 ELISA Kit (Sandwich ELISA) - LS-F8389 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 5.9 pg/ml Range 3.908-125 pg/ml

Human IL34 ELISA Kit (Sandwich ELISA) - LS-F10520 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 3.908-125 pg/ml

Mouse IL34 ELISA Kit (Sandwich ELISA) - LS-F10521 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 3.908-125 pg/ml

Human IL34 ELISA Kit (Sandwich ELISA) - LS-F11790 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 3.908-125 pg/ml

Human IL34 / Interleukin-34 ELISA Kit - RAB0699 from Sigma-Aldrich Category ELISA Kit Prices $633.00 Sizes 1 kt

Human IL-34 DuoSet ELISA, 15 Plate - DY5265 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 187.00 - 6,000 pg/mL

Human IL-34 Quantikine ELISA Kit - D3400 from R&D Systems Category ELISA Kit Prices $519.00 Sizes 1 kit Sensitivity 3.06 pg/mL Range 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Human Milk)

Quantikine Immunoassay Control Set 766 for Human IL-34 - QC31 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Mouse IL-34 Quantikine ELISA Kit - M3400 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 15.6 pg/mL Range 39.1 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

IL-34 ELISA Kit (Human) : 96 Wells (OKAG00148) - OKAG00148 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 188 pg/mL Range 188-6,000 pg/mL

Human Interleukin 34 ELISA Kit - abx152043 from Abbexa Category ELISA Kit Sensitivity 5.9 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Interleukin 34 (IL34), Human, ELISA Kit - SEC007Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 5.9pg/mL Range 15.6-1,000pg/mL

Interleukin 34, Human, ELISA Kit - E01I0388 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 50-1000pg/ml

Interleukin-34 (IL34), Human, ELISA Kit - CSB-EL011657HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Interleukin-34, IL34, Human, ELISA Kit - E2007h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Interleukin 34, IL-34, Mouse, ELISA Kit - E-EL-M0720 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Interleukin 34 (IL34), Human, CLIA Kit - SCC007Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 4.6pg/mL Range 15.6-1,000pg/mL

IL34 (Human) ELISA Kit - KA2217 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Human IL-34 ELISA - ELH-IL34 from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 7 pg/ml Range 7 pg/ml - 250 pg/ml

Human IL-34 ELISA MAX™ Deluxe - 439604 from Biolegend Category ELISA Kit Prices $330.00, $475.00, $695.00 Sizes 5 plates, 10 plates, 20 plates Sensitivity 33.4 pg/ml Range 78.1-5,000 pg/mL

LEGEND MAX™ Human IL-34 ELISA Kit with Pre-coated Plates - 439607 from Biolegend Category ELISA Kit Prices $425.00, $1,600.00 Sizes 1 pre-coated plate, 5 pre-coated plates Sensitivity 3.0 ± 5.2 pg/mL Range 78.1-5,000 pg/mL

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