IL34

Gene Symbol IL34
Entrez Gene 146433
Alt Symbol C16orf77, IL-34
Species Human
Gene Type protein-coding
Description interleukin 34
Other Description interleukin-34
Swissprots B2Z4A8 B2ZC70 B2RC28 Q8N6L2 Q6ZMJ4
Accessions EAW51800 EAW51801 EAW51802 Q6ZMJ4 AK172744 BAD18731 AK307727 AK308799 AK314913 BAG37425 AW292500 BC029804 AAH29804 BQ709387 CD248375 CD515627 EU599219 ACD13474 EU636994 ACD13452 XM_011522902 XP_011521204 XM_011522903 XP_011521205 XM_011522904 XP_011521206 NM_001172771 NP_001166242 NM_001172772 NP_001166243 NM_152456 NP_689669
Function Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. {ECO:0000269|PubMed:18467591, ECO:0000269|PubMed:20489731, ECO:0000269|PubMed:20504948, ECO:0000269|PubMed:20829061}.
Subcellular Location Secreted {ECO:0000269|PubMed:18467591}.
Tissue Specificity Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon. {ECO:0000269|PubMed:18467591}.

Human IL34 gene - orb91400 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Human

IL34 - MBS1276983 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC029804

Human IL34 cDNA clone(NM_001172771.1) - CDFH009196 from Creative Biomart

Species Human
Accession NM_001172771.1

Human IL34 cDNA clone(NM_001172772.1) - CDFH009197 from Creative Biomart

Species Human
Accession NM_001172772.1

Human IL34 ORF Clone(NM_001172771.1) - CDCR356677 from Creative Biomart

Species Human
Accession NM_001172771.1

Human IL34 ORF Clone(NM_001172771.1) - CDCR356678 from Creative Biomart

Species Human
Accession NM_001172771.1

Human IL34 ORF Clone(NM_001172772.1) - CDCR356680 from Creative Biomart

Species Human
Accession NM_001172772.1

Human IL34 ORF Clone(NM_001172772.1) - CDCR356685 from Creative Biomart

Species Human
Accession NM_001172772.1

Human IL34 Gene cDNA clone plasmid - HG10948-M from Sino Biological

Species Human

Human IL34 natural ORF mammalian expression plasmid - HG10948-UT from Sino Biological

Species Human
Accession NM_152456.1

Human IL34 ORF mammalian expression plasmid, C-GFPSpark tag - HG10948-ACG from Sino Biological

Species Human
Accession NM_152456.1

Human IL34 natural ORF mammalian expression plasmid, C-Myc tag - HG10948-CM from Sino Biological

Species Human
Accession NM_152456.1

Human IL34 ORF Clone(NM_001172772.1) - CDCR356680 from Creative biogene

Species Human

Human IL34 ORF clone (NM_001172771.1) - CDCL120613 from Creative biogene

Species Human

Human IL34 ORF Clone (BC029804) - CDCS409023 from Creative biogene

Species Human
Accession Q6ZMJ4

Human IL34 ORF clone (NM_152456.1) - CDCB157480 from Creative biogene

Species Human

Human IL34 cDNA Clone(NM_001172771.1) - CDFH009196 from Creative biogene

Species Human
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