ZKSCAN3

Gene Symbol ZKSCAN3
Entrez Gene 80317
Alt Symbol ZF47, ZFP306, ZNF306, ZNF309, ZSCAN13, ZSCAN35, Zfp47, dJ874C20.1, dJ874C20.1., zfp-47
Species Human
Gene Type protein-coding
Description zinc finger with KRAB and SCAN domains 3
Other Description zinc finger and SCAN domain-containing protein 13|zinc finger protein 306|zinc finger protein 309|zinc finger protein 47 homolog|zinc finger protein with KRAB and SCAN domains 3|zinc finger protein zfp47
Swissprots H7BXX1 B3KVC0 Q5VXH3 Q9H4T3 Q92972 B2R8W2 Q9BRR0
Accessions EAX03157 EAX03158 Q9BRR0 AK091225 BAG52311 AK122790 BAG53732 AK313532 BAG36309 BC006118 AAH06118 BM762243 BT007427 AAP36095 DA440043 DB214839 DN831452 U71601 AAB16813 XM_005249423 XP_005249480 XM_006715215 XP_006715278 XM_006715216 XP_006715279 XM_006715218 XP_006715281 XM_006715219 XP_006715282 NM_001242894 NP_001229823 NM_001242895 NP_001229824 NM_024493 NP_077819
Function Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas. {ECO:0000269|PubMed:18940803, ECO:0000269|PubMed:21057542, ECO:0000269|PubMed:22531714, ECO:0000269|PubMed:23434374}.
Subcellular Location Nucleus. Cytoplasm. Note=Mainly localizes in the nucleus. Under starvation conditions translocates to the cytoplasm, allowing expression of target genes involved in autophagy and lysosome biogenesis/function.

ZKSCAN3-Over-expression-Lysate - LY14179a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag ZKSCAN3 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ZKSCAN3 gene.

ZNF306 293T Cell Transient Overexpression Lysate(Denatured) - H00080317-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

ZKSCAN3 overexpression lysate - LY411284 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ZKSCAN3 Overexpression Lysate (Native) - NBP2-06334 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ZKSCAN3 Overexpression Lysate (Adult Normal) [NBP2-06334] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ZKSCAN3.

ZKSCAN3 Overexpression Lysate (Denatured) - H00080317-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human ZKSCAN3 Knockdown Stable Cell Line - CSC-DC017839 from Creative biogene

Category Cell Line
Species Human
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