UBE2C

Gene Symbol	UBE2C
Entrez Gene	11065
Alt Symbol	UBCH10, dJ447F3.2
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2C
Other Description	cyclin-selective ubiquitin carrier protein|mitotic-specific ubiquitin-conjugating enzyme|ubiquitin-conjugating enzyme E2 C|ubiquitin-protein ligase C
Swissprots	O00762 E1P5N7 A6NP33 G3XAB7
Accessions	EAW75804 EAW75805 EAW75806 EAW75807 EAW75808 EAW75809 O00762 AK311949 BAG34890 BC007656 AAH07656 BC016292 AAH16292 BC028161 BC032677 BC050736 AAH50736 BF974975 BI858659 BM556795 BM747513 BP227692 BT007300 AAP35964 BT007515 AAP36183 BT020165 AAV38967 BT020166 AAV38968 BU169315 BU171488 BU844974 CB143441 CK904708 CN354813 CN354815 CR456988 CAG33269 DB062573 DQ892416 ABM83342 DQ895630 ABM86556 EU831629 ACE87229 EU831714 ACE86548 U73379 AAB53362 NM_001281741 NP_001268670 NM_001281742 NP_001268671 NM_007019 NP_008950 NM_181799 NP_861515 NM_181800 NP_861516 NM_181801 NP_861517 NR_104036 NR_104037 NM_181802 NM_181803
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit. {ECO:0000269|PubMed:15558010, ECO:0000269|PubMed:18485873, ECO:0000269|PubMed:19820702, ECO:0000269|PubMed:19822757, ECO:0000269|PubMed:20061386}.
Top Pathways	Ubiquitin mediated proteolysis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UBE2C-Over-expression-Lysate - LY10065a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

UBE2C overexpression lysate - LY405592 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

UBE2C 293 Cell Lysate - 407611 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

UBE2C 293 Cell Lysate - 403657 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

UbcH10/UBE2C Overexpression Lysate (Native) - NBL1-17516 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

UbcH10/UBE2C Overexpression Lysate (Native) - NBL1-17514 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

UBE2C (h): 293 Lysate - sc-111903 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

UBE2C (h2): 293T Lysate - sc-116349 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

UBE2C (h4): 293T Lysate - sc-178107 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

UBE2C (h5): 293T Lysate - sc-178106 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

UBE2C Over-expression Lysate Product - GWB-9A921F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

UBE2C Over-expression Lysate Product - GWB-5BC078 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

UbcH10/UBE2C Overexpression Lysate (Native) - NBP2-04881 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human UBE2C Knockdown Stable Cell Line - CSC-DC016949 from Creative biogene Category Cell Line Species Human

Human UBE2C Knockout Cell Line-HeLa - CSC-RT1655 from Creative biogene Category Cell Line Species Human

UBE2C KO Cell Lysate-HeLa - CLKO-1502 from Creative biogene Category Cell Lysate

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