| Gene Symbol | UBE2C |
|---|---|
| Entrez Gene | 11065 |
| Alt Symbol | UBCH10, dJ447F3.2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ubiquitin-conjugating enzyme E2C |
| Other Description | cyclin-selective ubiquitin carrier protein|mitotic-specific ubiquitin-conjugating enzyme|ubiquitin-conjugating enzyme E2 C|ubiquitin-protein ligase C |
| Swissprots | O00762 E1P5N7 A6NP33 G3XAB7 |
| Accessions | EAW75804 EAW75805 EAW75806 EAW75807 EAW75808 EAW75809 O00762 AK311949 BAG34890 BC007656 AAH07656 BC016292 AAH16292 BC028161 BC032677 BC050736 AAH50736 BF974975 BI858659 BM556795 BM747513 BP227692 BT007300 AAP35964 BT007515 AAP36183 BT020165 AAV38967 BT020166 AAV38968 BU169315 BU171488 BU844974 CB143441 CK904708 CN354813 CN354815 CR456988 CAG33269 DB062573 DQ892416 ABM83342 DQ895630 ABM86556 EU831629 ACE87229 EU831714 ACE86548 U73379 AAB53362 NM_001281741 NP_001268670 NM_001281742 NP_001268671 NM_007019 NP_008950 NM_181799 NP_861515 NM_181800 NP_861516 NM_181801 NP_861517 NR_104036 NR_104037 NM_181802 NM_181803 |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit. {ECO:0000269|PubMed:15558010, ECO:0000269|PubMed:18485873, ECO:0000269|PubMed:19820702, ECO:0000269|PubMed:19822757, ECO:0000269|PubMed:20061386}. |
| Top Pathways | Ubiquitin mediated proteolysis |
Human-UBE2C-cDNA-Clone - DC02206 from Abgent, a WuXi AppTec company
|
||||||||
UBE2C cDNA (ANA10829) - ANA10829 from Aviva Systems Biology
|
||||||||
UBE2C - MBS1275107 from MyBioSource
|
||||||||
Human UBE2C cDNA clone(NM_181800.1) - CDFG011854 from Creative Biomart
|
||||||||
Human UBE2C cDNA clone(NM_181799.1) - CDFG011855 from Creative Biomart
|
||||||||
Human UBE2C cDNA clone(NM_181802.1) - CDFG011858 from Creative Biomart
|
||||||||
Human UBE2C cDNA clone(NM_181803.1) - CDFG011969 from Creative Biomart
|
||||||||
Human UBE2C cDNA clone(NM_007019.2) - CDFH020730 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_007019.2) - CDCL180266 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_007019.2) - CDCR294206 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_007019.2) - CDCR294207 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_007019.2) - CDCR294208 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_181799.1) - CDCR324229 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_181799.1) - CDCR324230 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_181800.1) - CDCR324231 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_181800.1) - CDCR324232 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_181802.1) - CDCR324236 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_181802.1) - CDCR324237 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_181803.1) - CDCR324238 from Creative Biomart
|
||||||||
Human UBE2C ORF Clone(NM_181803.1) - CDCR324239 from Creative Biomart
|
||||||||
human UBE2C ORF clone - CDCH097332 from Creative Biomart
|
||||||||
human UBE2C ORF clone - CDCH097333 from Creative Biomart
|
||||||||
human UBE2C ORF clone - CDCH097334 from Creative Biomart
|
||||||||
human UBE2C ORF clone - CDCH097335 from Creative Biomart
|
||||||||
human UBE2C ORF clone - CDCH097336 from Creative Biomart
|