Gene Symbol | MMP12 |
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Entrez Gene | 4321 |
Alt Symbol | HME, ME, MME, MMP-12 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 12 |
Other Description | macrophage metalloelastase|matrix metallopeptidase 12 (macrophage elastase)|matrix metalloproteinase 12 (macrophage elastase) |
Swissprots | B7ZLF6 B2R9X8 Q2M1L9 P39900 |
Accessions | AAB06314 AAB36943 AAW29944 EAW67033 P39900 AI343504 AI352562 AK313959 BAG36675 AW172994 BC112301 AAI12302 BC143773 AAI43774 BE440047 BE813419 HQ258263 ADR83017 L23808 AAA58658 NM_002426 NP_002417 |
Function | May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000305}. |
Tissue Specificity | Found in alveolar macrophages but not in peripheral blood monocytes. |
Human MMP12 ELISA Kit (Sandwich ELISA) - LS-F2781 from LifeSpan Bioscience
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Mouse MMP12 ELISA Kit (Sandwich ELISA) - LS-F2819 from LifeSpan Bioscience
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Human MMP12 ELISA Kit (Sandwich ELISA) - LS-F5249 from LifeSpan Bioscience
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Rat MMP12 ELISA Kit (Sandwich ELISA) - LS-F6123 from LifeSpan Bioscience
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Mouse MMP12 ELISA Kit (Sandwich ELISA) - LS-F6318 from LifeSpan Bioscience
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Mouse MMP12 ELISA Kit (Sandwich ELISA) - LS-F12052 from LifeSpan Bioscience
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Human MMP12 ELISA Kit (Sandwich ELISA) - LS-F12051 from LifeSpan Bioscience
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Human MMP-12 Luminex Performance Assay - LMP919B from R&D Systems
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Human MMP-12 Magnetic Luminex Performance Assay - LMPM919 from R&D Systems |
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Human MMP12 ELISA Kit - abx152350 from Abbexa
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Human MMP12 ELISA Kit - abx056275 from Abbexa
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Macrophage metalloelastase, MMP12, Human, ELISA Kit - E0402h from ARP American Research Products
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Matrix Metalloproteinase 12 (MMP-12), Human, ELISA Kit - CSB-E13208h from ARP American Research Products
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Matrix Metalloproteinase 12 (MMP12), Human, ELISA Kit - SEA402Hu from ARP American Research Products
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Matrix Metalloproteinase 12, MMP-12, Human, ELISA Kit - E-EL-H0133 from ARP American Research Products
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Neprilysin (MME), Human, ELISA Kit - E01N0530 from ARP American Research Products
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Neprilysin (NEP), Human, ELISA Kit - SEB785Hu from ARP American Research Products
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Neprilysin, MME, Human, ELISA Kit - E1785h from ARP American Research Products
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Matrix Metalloproteinase 12, MMP-12, Mouse, ELISA Kit - E-EL-M0075 from ARP American Research Products
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Matrix Metalloproteinase 12, MMP-12, Rat, ELISA Kit - E-EL-R0044 from ARP American Research Products
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Matrix Metalloproteinase 12, MMP-12, Rabbit, ELISA Kit - E-EL-RB0041 from ARP American Research Products
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Matrix Metalloproteinase 12, MMP-12, Chicken, ELISA Kit - E-EL-Ch2131 from ARP American Research Products
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Matrix Metalloproteinase 12, MMP-12, Porcine, ELISA Kit - E-EL-P0155 from ARP American Research Products
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Matrix Metalloproteinase 12, MMP-12, Guinea Pig, ELISA Kit - E-EL-GP1026 from ARP American Research Products
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Matrix Metalloproteinase 12, MMP-12, Monkey, ELISA Kit - E-EL-MK0196 from ARP American Research Products
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