MMP12

Gene Symbol MMP12
Entrez Gene 4321
Alt Symbol HME, ME, MME, MMP-12
Species Human
Gene Type protein-coding
Description matrix metallopeptidase 12
Other Description macrophage metalloelastase|matrix metallopeptidase 12 (macrophage elastase)|matrix metalloproteinase 12 (macrophage elastase)
Swissprots B7ZLF6 B2R9X8 Q2M1L9 P39900
Accessions AAB06314 AAB36943 AAW29944 EAW67033 P39900 AI343504 AI352562 AK313959 BAG36675 AW172994 BC112301 AAI12302 BC143773 AAI43774 BE440047 BE813419 HQ258263 ADR83017 L23808 AAA58658 NM_002426 NP_002417
Function May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000305}.
Tissue Specificity Found in alveolar macrophages but not in peripheral blood monocytes.

MMP-12 CRISPR/Cas9 KO Plasmid (h) - sc-401853 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MMP-12 HDR Plasmid (h) - sc-401853-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MMP-12 Double Nickase Plasmid (h) - sc-401853-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MMP-12 Double Nickase Plasmid (h2) - sc-401853-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MMP-12 CRISPR Activation Plasmid (h) - sc-401853-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MMP-12 CRISPR Activation Plasmid (h2) - sc-401853-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MMP-12 Lentiviral Activation Particles (h) - sc-401853-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MMP-12 Lentiviral Activation Particles (h2) - sc-401853-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MMP-12 siRNA (h) - sc-41557 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MMP-12 shRNA Plasmid (h) - sc-41557-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MMP-12 shRNA (h) Lentiviral Particles - sc-41557-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neprilysin/CD10 RNAi - H00004311-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Neprilysin/CD10 RNAi - H00004311-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU010651 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2082 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2082 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MMP12 siRNA (Human) - CRH2933 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MMP-12 RNAi - H00004321-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MMP12 (NM_002426.4) - SHH342888 from Creative biogene

Category siRNA
Species Reactivities Human

MMP12 shRNA Plasmid (Human) - CHH2933 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MMP12 miRNA 3'UTR clone - MiUTR3H-03838 from Creative biogene

Species Reactivities Human
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