MMP12

Gene Symbol	MMP12
Entrez Gene	4321
Alt Symbol	HME, ME, MME, MMP-12
Species	Human
Gene Type	protein-coding
Description	matrix metallopeptidase 12
Other Description	macrophage metalloelastase|matrix metallopeptidase 12 (macrophage elastase)|matrix metalloproteinase 12 (macrophage elastase)
Swissprots	B7ZLF6 B2R9X8 Q2M1L9 P39900
Accessions	AAB06314 AAB36943 AAW29944 EAW67033 P39900 AI343504 AI352562 AK313959 BAG36675 AW172994 BC112301 AAI12302 BC143773 AAI43774 BE440047 BE813419 HQ258263 ADR83017 L23808 AAA58658 NM_002426 NP_002417
Function	May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000305}.
Tissue Specificity	Found in alveolar macrophages but not in peripheral blood monocytes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MMP12 full length protein - ab131994 from Abcam Category Protein Source Wheat germ Species Human

Human MMP12 full length protein - ab151912 from Abcam Category Protein Source HEK 293 cells Species Human

Human MMP12 protein fragment - ab80209 from Abcam Category Protein Source E. coli Species Human

MMP12 peptide - ab41081 from Abcam Category Peptide

MMP12 peptide - ab41085 from Abcam Category Peptide

MMP12 peptide - ab41086 from Abcam Category Peptide

MMP12 peptide - ab41087 from Abcam Category Peptide

MMP12 peptide - ab44021 from Abcam Category Peptide

MME / CD10 Antibody Blocking Peptide - LS-E102 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MME / CD10 Antibody Blocking Peptide - LS-E8867 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MME / CD10 Antibody Blocking Peptide - LS-E8868 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MME / CD10 Antibody Blocking Peptide - LS-E23109 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MMP12 Antibody Blocking Peptide - LS-E8123 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MMP12 Antibody Blocking Peptide - LS-E27288 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Neprilysin/CD10 Protein - H00004311-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MMP-12 Protein - H00004321-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Neprilysin/CD10 Recombinant Protein - H00004311-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human MMP-12 Protein - H00004321-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

MMP-12 Peptide - P1804 from Novus Biologicals Category Peptide Species Human

Recombinant Human Neprilysin/CD10 Protein - H00004311-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

MMP12-Antibody-C-term-Blocking-Peptide - BP6196a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MMP12 blocking peptide - GTX88142-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Bovine

Recombinant Human MMP-12, CF - 917-MP-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu17-Cys470

Recombinant Human MMP-12 Western Blot Standard Protein - WBC019 from R&D Systems Category Protein Prices $109.00 Sizes 1 vial Species Human

Human MMP12 protein - orb49533 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source HEK293

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