Gene Symbol | DGKE |
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Entrez Gene | 8526 |
Alt Symbol | DAGK5, DAGK6, DGK, NPHS7 |
Species | Human |
Gene Type | protein-coding |
Description | diacylglycerol kinase, epsilon 64kDa |
Other Description | DAG kinase epsilon|DGK-epsilon|diacylglycerol kinase epsilon|diglyceride kinase epsilon |
Swissprots | P52429 Q8TBM4 Q9UKQ3 |
Accessions | AAD45666 EAW94526 P52429 AB209365 BAD92602 AK057591 AK129803 AK293039 BAF85728 AK310668 AL555194 BC022297 AAH22297 BC130629 AAI30630 BC130631 AAI30632 BM682264 DB221284 HQ258315 ADR83069 U49379 AAC50497 XM_011525394 XP_011523696 XM_011525395 XP_011523697 XM_011525396 XP_011523698 XM_011525397 XP_011523699 XM_011525398 XP_011523700 XR_934581 NM_003647 NP_003638 |
Function | Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Membrane {ECO:0000269|PubMed:23542698}. Cytoplasm {ECO:0000269|PubMed:23542698}. |
Tissue Specificity | Expressed predominantly in testis. Expressed in endothelium, platelets and podocytes (at protein level). {ECO:0000269|PubMed:23542698}. |
Top Pathways | Choline metabolism in cancer, Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system |
Human DGKE full length protein - ab160073 from Abcam
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Human DGKE protein fragment - ab160074 from Abcam
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DGKE / DGK Epsilon Antibody Blocking Peptide - LS-E16622 from LifeSpan Bioscience
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Recombinant Human DGK-epsilon Protein - H00008526-P01 from Novus Biologicals
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Recombinant Human DGK-epsilon Protein - H00008526-Q01 from Novus Biologicals
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Recombinant Human DGK-epsilon Protein - H00008526-G01-10ug from Novus Biologicals
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DGK-epsilon Peptide - NBP1-19576PEP from Novus Biologicals
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DGKE Blocking Peptide - 33R-2256 from Fitzgerald
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Human DGKe Protein - abx066316 from Abbexa
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DAG kinase epsilon - H00008526-P01-10 from Acris Antibodies
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DAG kinase epsilon - H00008526-P01-25 from Acris Antibodies
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DAG kinase epsilon - H00008526-Q01-10 from Acris Antibodies
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DAG kinase epsilon - H00008526-Q01-25 from Acris Antibodies
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DGKE fusion protein - ag2512 from Proteintech Group
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Recombinant Diacylglycerol Kinase Epsilon (DGKe) - RPE848Hu01 from Uscn Life Science Inc.
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DGK epsilon Blocking Peptide - CBP3898 from Cohesion Biosciences
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DGK-ε (S194) Peptide - BS2281P from Bioworld Technology
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Recombinant Diacylglycerol Kinase Epsilon (DGKe) - RPE848Hu01 from Cloud-clone
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Recombinant Diacylglycerol Kinase Zeta (DGKz) - RPE854Hu01 from Cloud-clone
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Diacylglycerol Kinase Epsilon (DGKe) - RPU141180 from Biomatik
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DGKE Protein - abx164074 from Abbexa
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DAG kinase epsilon - TP319913 from Acris Antibodies
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DGK-epsilon Recombinant Protein Antigen - NBP1-85315PEP from Novus Biologicals
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DGK epsilon Blocking Peptide - abx162391 from Abbexa
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DGKE-Antibody-C-term-Blocking-Peptide - BP8125b from Abgent, a WuXi AppTec company
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