Gene Symbol | DGKE |
---|---|
Entrez Gene | 8526 |
Alt Symbol | DAGK5, DAGK6, DGK, NPHS7 |
Species | Human |
Gene Type | protein-coding |
Description | diacylglycerol kinase, epsilon 64kDa |
Other Description | DAG kinase epsilon|DGK-epsilon|diacylglycerol kinase epsilon|diglyceride kinase epsilon |
Swissprots | P52429 Q8TBM4 Q9UKQ3 |
Accessions | AAD45666 EAW94526 P52429 AB209365 BAD92602 AK057591 AK129803 AK293039 BAF85728 AK310668 AL555194 BC022297 AAH22297 BC130629 AAI30630 BC130631 AAI30632 BM682264 DB221284 HQ258315 ADR83069 U49379 AAC50497 XM_011525394 XP_011523696 XM_011525395 XP_011523697 XM_011525396 XP_011523698 XM_011525397 XP_011523699 XM_011525398 XP_011523700 XR_934581 NM_003647 NP_003638 |
Function | Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Membrane {ECO:0000269|PubMed:23542698}. Cytoplasm {ECO:0000269|PubMed:23542698}. |
Tissue Specificity | Expressed predominantly in testis. Expressed in endothelium, platelets and podocytes (at protein level). {ECO:0000269|PubMed:23542698}. |
Top Pathways | Choline metabolism in cancer, Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system |
DGK-ε siRNA (h) - sc-38989 from Santa Cruz Biotechnology
|
||||||||
DGK-ε shRNA Plasmid (h) - sc-38989-SH from Santa Cruz Biotechnology
|
||||||||
DGK-ε shRNA (h) Lentiviral Particles - sc-38989-V from Santa Cruz Biotechnology
|
||||||||
DGK-epsilon RNAi - H00008526-R03 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU031341 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK0578 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK0577 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK0579 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN7181 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7181 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR06640 from Sigma-Aldrich
|
||||||||
DGKE siRNA (Human) - CRH5597 from Cohesion Biosciences
|
||||||||
DGKE - MBS8222794 from MyBioSource
|
||||||||
shRNA set against Human DGKE (NM_003647.2) - SHH277481 from Creative biogene
|
||||||||
Human DGKE siRNA - orb266099 from Biorbyt
|
||||||||
DGKE shRNA Plasmid (Human) - CHH5597 from Cohesion Biosciences
|