CIR1

Gene Symbol CIR1
Entrez Gene 9541
Alt Symbol CIR
Species Human
Gene Type protein-coding
Description corepressor interacting with RBPJ, 1
Other Description CBF1 interacting corepressor|CBF1-interacting corepressor|corepressor interacting with RBPJ 1|recepin
Swissprots A8K8M4 Q8IWI2 Q86X95 Q4G1B9 Q12804 A6NFI6 Q6PJI4 O95367
Accessions AAY24216 EAX11144 EAX11145 EAX11146 Q86X95 AF098297 AAD05243 AK292389 BAF85078 BC015040 BC021175 AAH21175 BC031018 AAH31018 BC038987 AAH38987 BC046098 AAH46098 BU596189 U03644 AAA17853 NM_199075 NM_004882 NP_004873
Function May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription. {ECO:0000250, ECO:0000269|PubMed:19409814, ECO:0000269|PubMed:9874765}.
Subcellular Location Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome.
Tissue Specificity Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas. {ECO:0000269|PubMed:9874765}.
Top Pathways Notch signaling pathway

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7230744 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7235884 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7201098 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7223383 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7236475 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7230867 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7236530 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7244999 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7239398 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Corepressor interacting with RBPJ 1 (CIR), ELISA Kit - MBS7213307 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Recepin (CIR), ELISA Kit - MBS9311191 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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